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Continuous glucose monitoring in neonates: challenges and opportunities
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Open AccessBloodstream Infection Due to a VIM-Metallo-β-Lactamase-Producing Klebsiella pneumoniae Treated with Cefiderocol in a Preterm Newborn
The prevalence of certain multidrug-resistant organisms (MDROs), especially Gram-negative bacteria, is dramatically increasing in patient care settings, including pediatric and neonatal units. However, most of...
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Article
Open AccessHeart rate cut-offs to identify non-febrile children with dehydration and acute kidney injury
We hypothesized that the heart rate (HR) variation in an acute setting compared with HR in wellbeing status could be a good marker of both dehydration and acute kidney injury (AKI). Since HR in wellbeing statu...
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Open AccessImpact of intrauterine growth restriction on cerebral and renal oxygenation and perfusion during the first 3 days after birth
Intrauterine growth restriction (IUGR) is associated with a higher incidence of perinatal complications as well as cardiovascular and renal diseases later on. A better insight into the disease mechanisms under...
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Open AccessEffect of intra-partum Oxytocin on neonatal encephalopathy: a systematic review and meta-analysis
Oxytocin is widely used for induction and augmentation of labour, particularly in low- and middle-income countries (LMICs). In this systematic review and meta-analysis, we examined the effect of intra-partum O...
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Open AccessErythropoietin monotherapy for neuroprotection after neonatal encephalopathy in low-to-middle income countries: a systematic review and meta-analysis
We examined whether erythropoietin monotherapy improves neurodevelopmental outcomes in near-term and term infants with neonatal encephalopathy (NE) in low-middle income countries (LMICs).
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The use of gene expression as a disease stratification tool of neonatal encephalopathy
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Open AccessTranscriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy
A rapid and early diagnostic test to identify the encephalopathic babies at risk of adverse outcome may accelerate the development of neuroprotectants. We examined if a whole blood transcriptomic signature mea...
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Early Career Investigator—August 2020
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Continuous glucose monitoring profile during therapeutic hypothermia in encephalopathic infants with unfavorable outcome
The relation between glucose homeostasis and outcome in hypoxic-ischemic encephalopathy (HIE) is unclear. To investigate whether glucose abnormalities assessed by using continuous interstitial glucose monitori...
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Prospective research in infants with mild encephalopathy identified in the first six hours of life: neurodevelopmental outcomes at 18–22 months
Studies of early childhood outcomes of mild hypoxic-ischemic encephalopathy (HIE) identified in the first 6 h of life are lacking.
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Open AccessHypothermia for encephalopathy in low and middle-income countries (HELIX): study protocol for a randomised controlled trial
Therapeutic hypothermia reduces death and disability after moderate or severe neonatal encephalopathy in high-income countries and is used as standard therapy in these settings. However, the safety and efficac...
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Presepsin for the detection of early-onset sepsis in preterm newborns
Early-onset sepsis (EOS) is responsible for an important fraction of neonatal morbidity and mortality all over the world. The aim of this study was to assess whether presepsin (P-SEP) can be a more accurate bi...
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Small renal size in newborns with spina bifida: possible causes
Previous studies reported that children with neural tube defects, but without any history of intrinsic renal diseases, have small kidneys when compared with age-matched standard renal growth. The aim of this s...
