4 Result(s)

Article

Selection and characterization of human scFvs targeting the SARS-CoV-2 nucleocapsid protein isolated from antibody libraries of COVID-19 patients

In 2019, the novel SARS-CoV-2 coronavirus emerged in China, causing the pneumonia named COVID-19. At the beginning, all research efforts were focused on the spike (S) glycoprotein. However, it became evident t...

Simonetta Lisi, Francesca Malerba, Paola Quaranta, Rita Florio… in Scientific Reports (2024)

Article

Specialized metabolites from plants as a source of new multi-target antiviral drugs: a systematic review

Viral infections have always been the main global health challenge, as several potentially lethal viruses, including the hepatitis virus, herpes virus, and influenza virus, have affected human health for decad...

Maria Ponticelli, Maria Laura Bellone, Valentina Parisi… in Phytochemistry Reviews (2023)

Article

Publisher Correction: Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin

Michele Lai, Rachele Amato, Veronica La Rocca, Mesut Bilgin… in Scientific Reports (2021)

Article

Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin

Acid ceramidase (AC) is a lysosomal hydrolase encoded by the ASAH1 gene, which cleaves ceramides into sphingosine and fatty acid. AC is expressed at high levels in most human melanoma cell lines and may confer re...

Michele Lai, Rachele Amato, Veronica La Rocca, Mesut Bilgin… in Scientific Reports (2021)