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  1. Article

    Open Access

    Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L

    Antiangiogenic treatment targeting the vascular endothelial growth factor (VEGF) pathway is a powerful tool to combat tumor growth and progression; however, drug resistance frequently emerges. We identify CD5L...

    Christopher J. LaFargue, Paola Amero, Kyunghee Noh… in Nature Communications (2023)

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  2. No Access

    Article

    Targeting CDK7 reverses tamoxifen resistance through regulating stemness in ER+ breast cancer

    Although tamoxifen is the mainstay endocrine therapy for estrogen receptor-positive (ER+) breast cancer patients, the emergence of tamoxifen resistance is still the major challenge that results in treatment fa...

    Yasmin M. Attia, Salama A. Salama, Samia A. Shouman… in Pharmacological Reports (2022)