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Article
Open AccessThe promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)
There is growing evidence supporting a role for microRNAs (miRNA) as targets in aberrant mechanisms of DNA hypermethylation. Epigenetic silencing of tumor suppressor miRNAs, including miR-663, which has recent...
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Article
Open AccessInhibition of the ecto-beta subunit of F1F0-ATPase inhibits proliferation and induces apoptosis in acute myeloid leukemia cell lines
Leukemia, a heterogeneous clonal disorder of hematopoietic progenitor cells, presents a world-wide health problem, especially in childhood. F1F0 ATPase, an inner mitochondrial enzyme, is expressed on the plasm...
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Article
Open AccessAnalyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays
The Real-time PCR Array System is the ideal tool for analyzing the expression of a focused panel of genes. In this study, we will analyze the gene expression profile of pediatric acute myeloid leukemia with re...
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Article
Open AccessMMP28 (epilysin) as a novel promoter of invasion and metastasis in gastric cancer
The purpose of this study was to investigate invasion and metastasis related genes in gastric cancer.
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Article
Open AccessRetinoic acid induces HL-60 cell differentiation via the upregulation of miR-663
Differentiation of the acute myeloid leukemia (AML) cell line HL-60 can be induced by all trans-retinoic acid (ATRA); however, the mechanism regulating this process has not been fully characterized.
