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Article
Open AccessShared genetic factors and causal association between chronic hepatitis C infection and diffuse large B cell lymphoma
Epidemiological research and systematic meta-analyses indicate a higher risk of B-cell lymphomas in patients with chronic hepatitis C virus (HCV) compared to non-infected individuals. However, the genetic link...
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Article
A review of type 3 Gaucher disease: unique neurological manifestations and advances in treatment
Gaucher disease (GD) is a rare lysosomal storage disease that is caused by mutations in the GBA gene. It is classified into three main phenotypes according to the patient’s clinical presentation. Of these, chroni...
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Article
Open AccessMolecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration
Intervertebral disc degeneration (IVDD) is the major cause of low-back pain. Histone deacetylase 9 (HDAC9) was dramatically decreased in the degenerative nucleus pulposus (NP) samples of patients with interver...
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Article
Causal relationships between circulating inflammatory cytokines and diffuse large B cell lymphoma: a bidirectional Mendelian randomization study
Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Studies indicated that inflammatory cytokines involved in the occurrence and progression of DLBCL and it is challenging to...
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Article
Open AccessIs abaloparatide more efficacious on increasing bone mineral density than teriparatide for women with postmenopausal osteoporosis? An updated meta-analysis
Osteoporosis poses a challenge to public health, causing fragility fractures, especially in postmenopausal women. Abaloparatide (ABL) is an effective anabolic agent to improve bone formation and resorption amo...
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Article
Open AccessPlating versus elastic stable intramedullary nailing for displaced pediatric midshaft clavicular fractures
Traditionally, operative treatment for displaced midshaft clavicle fractures in adolescents has been achieved by using a plate and screws. However, a minimally invasive trend has led surgeons to use the elasti...
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Article
Open AccessThe Clinical Characteristics and Prognosis of Chinese Patients with Light-Chain Amyloidosis: A Retrospective Multicenter Analysis
To retrospectively identify the critical characteristics and prognostic factors of light-chain amyloidosis. Patients and Methods: Data were collected and compared from 91 patients who were diagnosed with light...
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Article
Open Access3D-printed model and osteotomy template technique compared with conventional closing-wedge osteotomy in cubitus varus deformity
Cubitus varus deformity is the most common late complication of malunited supracondylar fracture that requires corrective osteotomy and fixation. From 2009 to 2017, 40 consecutive patients with cubitus varus d...
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Article
Open AccessGlenohumeral joint dislocation is rare in children with proximal humeral fractures: a descriptive study and literature review
Glenohumeral dislocation combined with fracture of the proximal humerus is extremely rare in children, and this study aims to investigate its incidence in the pediatric population and review the treatment stra...
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Article
Open AccessExternal fixation versus elastic stable intramedullary nailing in the treatment of open tibial shaft fractures in children
External fixator (EF) is a popular choice for open tibial fractures, but pin tract infection (PTI) and refracture are common complications. Elastic stable intramedullary nail (ESIN) has been reported in the tr...
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Article
Open AccessGenome-wide identification of key regulatory lncRNAs in esophageal cancer metastasis
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Article
Open AccessIntra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty
The optimal dosage and administration approach of tranexamic acid (TXA) in primary total knee arthroplasty (TKA) remains controversial. In light of recently published 14 randomized controlled trials (RCTs), th...
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Article
Open AccessBiodegradable pins for lateral condylar fracture of the humerus with an early delayed presentation in children: a retrospective study of biodegradable pin vs. Kirschner wire
The clinical outcome of open reduction and internal fixation (ORIF) for delayed lateral condylar fracture of the humerus (LCFH) varies in different studies, but ORIF for LCFH with an early-delayed presentation...
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Article
Open AccessAdvances in targeted therapy for esophageal cancer
Esophageal cancer (EC) is one of the most lethal cancers in the world, and its morbidity and mortality rates rank among the top ten in China. Currently, surgical resection, radiotherapy and chemotherapy are th...
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Article
Open AccessPediatric physeal slide-traction plate fixation for pathological distal femoral fracture caused by unicameral bone cyst in adolescents
Most patients suffering from distal femoral unicameral bone cysts (UBCs) are adolescents that require an early return to normal activities, including school attendance and sports exercises. However, the optima...
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Article
Open AccessEchinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors with poor survival. It is urgent to search for new efficient drugs with good stability and safety for clinical therapy. This...
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Article
Open AccessOne additional shot of brachial plexus block equates to less postoperative pain for younger children with elbow surgeries
Postoperative pain in children has always been inadequately evaluated. This study aims to evaluate the postoperative pain response using an additional dose of brachial plexus block (BPB) for younger children r...
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Article
Open AccessFixation of delayed distal radial fracture involving metaphyseal diaphyseal junction in adolescents: a comparative study of crossed Kirschner-wiring and non-bridging external fixator
Conservative treatment remains the preferred choice for distal radius fracture in children. However, loss of reduction is problematic, especially in an older child. Crossed Kirschner-wires is widely used to tr...
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Article
Open AccessEnhanced recovery care versus traditional non-ERAS care following osteotomies in developmental dysplasia of the hip in children: a retrospective case-cohort study
Enhanced recovery after surgery (ERAS) has been shown to shorten the length of hospital stay and reduce the incidence of perioperative complications in many surgical fields. However, there has been a paucity o...
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Chapter and Conference Paper
Key Technologies for Square/Round Billet Continuous Casting
According to the problems of bad castability of molten steel, surface longitudinal cracks and the difficulty of elimination for internal defects of billet in rolling process, the technologies of continuous cas...