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Article
Open AccessTakayasu arteritis presenting as cerebral aneurysms in an 18 month old: A case report
Central nervous system involvement occurs in as many as twenty percent of Takayasu arteritis cases. When central nervous system disease is present, it typically manifests as cerebral ischemia or stroke. There ...
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Article
Open AccessThe pediatric rheumatology quality of life scale: validation of the English version in a US cohort of juvenile idiopathic arthritis
This study aims to validate the English version of the Pediatric Rheumatology Quality of Life Scale (PRQL), a concise Health Related Quality of Life (HRQoL) measure, in a US cohort of children with juvenile id...
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Living Reference Work Entry In depth
Henoch-Schönlein Purpura
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Article
Ultrasound of the joints and entheses in healthy children
Tendon insertion pathologies such as enthesitis and apophysitis in children can result from trauma, overuse syndrome and arthritis. Knowledge of the US appearance of normal joints by age might aid diagnosis of...
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Reference Work Entry In depth
Henoch-Schönlein Purpura
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Article
Open AccessProceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting
P1 Serologic evidence of gut-driven systemic inflammation in juvenile idiopathic arthritis
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Article
Imaging in Juvenile Spondyloarthritis
This review aims to provide an update on the use of imaging in the assessment of juvenile spondyloarthritis (JSpA) disease manifestations.
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Article
Open AccessPilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans
To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans (CTPs) for systemic Juvenile Idiopathic Arthr...
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Article
Open AccessMulticenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches
Enthesitis-related arthritis (ERA) is a specific subtype of juvenile idiopathic arthritis (JIA) defined according to the International League of Associations for Rheumatology (ILAR) criteria. We aimed to chara...
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Article
Open AccessAge and fecal microbial strain-specific differences in patients with spondyloarthritis
Prior studies have demonstrated abnormalities in the composition of the gastrointestinal microbiota in pediatric and adult patients with spondyloarthritis (SpA). In particular, diminished fecal abundance of Faeca...
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Article
Open AccessFeasibility and reliability of the Spondyloarthritis Research Consortium of Canada sacroiliac joint inflammation score in children
Published methods for quantification of magnetic resonance imaging (MRI) evidence of inflammation in the sacroiliac joint lack validation in pediatric populations. We evaluated the reliability and construct va...
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Article
Open AccessThe American English version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)
The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic ...
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Article
Open AccessUse of rituximab and risk of re-hospitalization for children with neuromyelitis optica spectrum disorder
Treatment algorithms for neuromyelitis optica spectrum disorder (NMOSD) vary, and sparse data exist regarding the impact of initial treatments on disease course. We aimed to determine whether administration of...
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Article
Open AccessRadiographs in screening for sacroiliitis in children: what is the value?
We aimed to evaluate the diagnostic utility of pelvic radiographs versus magnetic resonance imaging (MRI) of the sacroiliac joints in children with suspected sacroiliitis.
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Article
Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis
Studies have identified abnormalities in the microbiota of patients with arthritis. To evaluate the pathogenicity of human microbiota, we performed fecal microbial transplantation from children with spondyloar...
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Article
Echocardiographic Assessment of Diastolic Function in Children with Incident Systemic Lupus Erythematosus
The timing and etiology of diastolic impairment in pediatric-onset systemic lupus erythematosus (SLE) are poorly understood. We compared echocardiographic metrics of left ventricular diastolic function in chil...
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Article
Open AccessSpondyloarthritis Research Consortium of Canada sacroiliac joint inflammation and structural scores: change score reliability and recalibration utility in children
The SPARCC sacroiliac joint inflammation (SIS) and structural (SSS) scores are reliable measures to quantify abnormalities in the pediatric sacroiliac joint. We aimed to evaluate the utility of online calibrat...
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Article
Open AccessNocturnal blood pressure dip** as a marker of endothelial function and subclinical atherosclerosis in pediatric-onset systemic lupus erythematosus
Loss of the normal nocturnal decline in blood pressure (BP), known as non-dip**, is a potential measure of cardiovascular risk identified by ambulatory blood pressure monitoring (ABPM). We sought to determin...
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Article
Open AccessJuvenile Spondyloarthritis: focus on uveitis
Juvenile spondyloarthritis (JSpA) represents a group of inflammatory arthritides with several distinctive features (enthesitis, involvement of spine and sacroiliac joint, HLA-B27 association and development of...
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Article
Normal hip joint fluid volumes in healthy children of different ages, based on MRI volumetric quantitative measurement
While magnetic resonance imaging (MRI) of the pelvis and hips is common in pediatric patients, to date there are no data on the quantification of normal hip joint fluid volume in this patient population.
