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Article
Underutilization of ambulatory blood pressure monitoring in locally and nationally representative samples of patients with childhood-onset systemic lupus erythematosus
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Article
Open AccessBiologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA): study protocol for a randomized pragmatic trial
The effectiveness of biologic therapies, primarily tumor necrosis factor inhibitors (TNFi), for children with spondyloarthritis (SpA) has made inactive disease a realistic patient outcome. However, biologic th...
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Living Reference Work Entry In depth
Chronic Nonbacterial Osteomyelitis
Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disorder of children and young adults. CNO is used as an umbrella term that fits a clinical spectrum of disease which may include a sporadic...
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Article
Open AccessEvaluation of pediatric rheumatology telehealth satisfaction during the COVID-19 pandemic
During the Coronavirus disease 2019 pandemic, ambulatory pediatric rheumatology healthcare rapidly transformed to a mainly telehealth model. However, pediatric patient and caregiver satisfaction with broadly d...
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Article
Open AccessChanges over time in inflammatory and structural lesions at the sacroiliac joint in children with spondyloarthritis exposed and unexposed to tumor necrosis factor inhibitor
The objective of this work was to describe magnetic resonance imaging (MRI) changes over time in inflammatory and structural lesions at the sacroiliac joint (SIJ) in children with spondyloarthritis (SpA) expos...
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Article
Open AccessEffect of first-line biologic initiation on glucocorticoid exposure in children hospitalized with new-onset systemic juvenile idiopathic arthritis: emulation of a pragmatic trial using observational data
Glucocorticoid exposure is a significant driver of morbidity in children with systemic juvenile idiopathic arthritis (sJIA). We determined the effect of early initiation of biologic therapy (IL-1 or IL-6 inhib...
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Article
Open AccessDo geography and ethnicity play a role in juvenile Spondyloarthritis? A multi-center binational retrospective study
Observations among Israeli pediatric rheumatologists reveal that pediatric Juvenile Spondyloarthritis (JSpA) may present differently compared to patients from the United States (US). This study is aimed to com...
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Article
Open AccessSuicidal risk and resilience in juvenile fibromyalgia syndrome: a cross-sectional cohort study
To characterize suicidality among youth with juvenile fibromyalgia syndrome (JFMS) receiving treatment from pediatric rheumatologists at a tertiary care center in order to determine the prevalence of suicidali...
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Article
Open AccessLongitudinal assessment of racial disparities in juvenile idiopathic arthritis disease activity in a treat-to-target intervention
We sought to evaluate racial disparities in disease outcomes among children with polyarticular juvenile idiopathic arthritis (JIA) during a treat-to-target (TTT) intervention with clinical decision support (CDS).
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Article
Open AccessDeterminants of disease activity change over time in Enthesitis related arthritis: effect of structured outcome monitoring and clinical decision support
We aimed to test if standardized point-of-care outcome monitoring and clinical decision support (CDS), as compared to standard care, improves disease activity and patient-reported pain in children with enthesi...
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Article
Normal hip joint fluid volumes in healthy children of different ages, based on MRI volumetric quantitative measurement
While magnetic resonance imaging (MRI) of the pelvis and hips is common in pediatric patients, to date there are no data on the quantification of normal hip joint fluid volume in this patient population.
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Article
Open AccessJuvenile Spondyloarthritis: focus on uveitis
Juvenile spondyloarthritis (JSpA) represents a group of inflammatory arthritides with several distinctive features (enthesitis, involvement of spine and sacroiliac joint, HLA-B27 association and development of...
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Article
Open AccessNocturnal blood pressure dip** as a marker of endothelial function and subclinical atherosclerosis in pediatric-onset systemic lupus erythematosus
Loss of the normal nocturnal decline in blood pressure (BP), known as non-dip**, is a potential measure of cardiovascular risk identified by ambulatory blood pressure monitoring (ABPM). We sought to determin...
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Article
Open AccessSpondyloarthritis Research Consortium of Canada sacroiliac joint inflammation and structural scores: change score reliability and recalibration utility in children
The SPARCC sacroiliac joint inflammation (SIS) and structural (SSS) scores are reliable measures to quantify abnormalities in the pediatric sacroiliac joint. We aimed to evaluate the utility of online calibrat...
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Article
Echocardiographic Assessment of Diastolic Function in Children with Incident Systemic Lupus Erythematosus
The timing and etiology of diastolic impairment in pediatric-onset systemic lupus erythematosus (SLE) are poorly understood. We compared echocardiographic metrics of left ventricular diastolic function in chil...
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Article
Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis
Studies have identified abnormalities in the microbiota of patients with arthritis. To evaluate the pathogenicity of human microbiota, we performed fecal microbial transplantation from children with spondyloar...
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Article
Open AccessRadiographs in screening for sacroiliitis in children: what is the value?
We aimed to evaluate the diagnostic utility of pelvic radiographs versus magnetic resonance imaging (MRI) of the sacroiliac joints in children with suspected sacroiliitis.
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Article
Open AccessUse of rituximab and risk of re-hospitalization for children with neuromyelitis optica spectrum disorder
Treatment algorithms for neuromyelitis optica spectrum disorder (NMOSD) vary, and sparse data exist regarding the impact of initial treatments on disease course. We aimed to determine whether administration of...
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Article
Open AccessThe American English version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)
The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic ...
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Article
Open AccessFeasibility and reliability of the Spondyloarthritis Research Consortium of Canada sacroiliac joint inflammation score in children
Published methods for quantification of magnetic resonance imaging (MRI) evidence of inflammation in the sacroiliac joint lack validation in pediatric populations. We evaluated the reliability and construct va...
