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  1. Article

    Open Access

    Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites

    Activation-induced cytidine deaminase (AID) triggers antibody diversification in B cells by catalysing deamination and subsequently mutating immunoglobulin (Ig) genes. Association of AID with RNA Pol II and oc...

    Virginia C. Rodríguez-Cortez, Paloma Martínez-Redondo… in Scientific Reports (2017)

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  2. No Access

    Protocol

    Methods to Study the Role of Sirtuins in Genome Stability

    One of the most important roles of Sirtuins is to ensure the maintenance of genome integrity under stress conditions. In this chapter, we provide a methodology to study this role of Sirtuins at two different l...

    Paloma Martínez-Redondo, Alejandro Vaquero in Sirtuins (2013)