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  1. Article

    Open Access

    Reusability report: Unpaired deep-learning approaches for holographic image reconstruction

    Deep-learning methods using unpaired datasets hold great potential for image reconstruction, especially in biomedical imaging where obtaining paired datasets is often difficult due to practical concerns. A rec...

    Yuhe Zhang, Tobias Ritschel, Pablo Villanueva-Perez in Nature Machine Intelligence (2024)

  2. Article

    Open Access

    Dose-efficient scanning Compton X-ray microscopy

    The highest resolution of images of soft matter and biological materials is ultimately limited by modification of the structure, induced by the necessarily high energy of short-wavelength radiation. Imaging th...

    Tang Li, J. Lukas Dresselhaus, Nikolay Ivanov in Light: Science & Applications (2023)

  3. Article

    Open Access

    Ultracompact 3D microfluidics for time-resolved structural biology

    To advance microfluidic integration, we present the use of two-photon additive manufacturing to fold 2D channel layouts into compact free-form 3D fluidic circuits with nanometer precision. We demonstrate this ...

    Juraj Knoška, Luigi Adriano, Salah Awel, Kenneth R. Beyerlein in Nature Communications (2020)

  4. Article

    Open Access

    Megahertz serial crystallography

    The new European X-ray Free-Electron Laser is the first X-ray free-electron laser capable of delivering X-ray pulses with a megahertz inter-pulse spacing, more than four orders of magnitude higher than previou...

    Max O. Wiedorn, Dominik Oberthür, Richard Bean, Robin Schubert in Nature Communications (2018)

  5. Article

    Open Access

    X-ray focusing with efficient high-NA multilayer Laue lenses

    Multilayer Laue lenses are volume diffraction elements for the efficient focusing of X-rays. With a new manufacturing technique that we introduced, it is possible to fabricate lenses of sufficiently high numer...

    Saša Bajt, Mauro Prasciolu, Holger Fleckenstein in Light: Science & Applications (2018)

  6. Article

    Open Access

    A generalized quantitative interpretation of dark-field contrast for highly concentrated microsphere suspensions

    In X-ray grating interferometry, dark-field contrast arises due to partial extinction of the detected interference fringes. This is also called visibility reduction and is attributed to small-angle scattering ...

    Spyridon Gkoumas, Pablo Villanueva-Perez, Zhentian Wang, Lucia Romano in Scientific Reports (2016)