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2 Result(s)

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  1. Article

    Open Access

    Tackling antibiotic resistance by inducing transient and robust collateral sensitivity

    Collateral sensitivity (CS) is an evolutionary trade-off traditionally linked to the mutational acquisition of antibiotic resistance (AR). However, AR can be temporally induced, and the possibility that this c...

    Sara Hernando-Amado, Pablo Laborda, José Luis Martínez in Nature Communications (2023)

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  2. Article

    Open Access

    Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance

    Mutations in mexZ, encoding a negative regulator of the expression of the mexXY efflux pump genes, are frequently acquired by Pseudomonas aeruginosa at early stages of lung infection. Although traditionally relat...

    Pablo Laborda, Signe Lolle, Sara Hernando-Amado… in Nature Communications (2024)

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