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Article
A comparative study on antibodies to nucleoli and 5-hydroxytryptamine in patients with fibromyalgia syndrome and tryptophan-induced eosinophilia-myalgia syndrome
Eosinophilia myalgia syndrome (EMS) has been related to intake of “contaminated” L-tryptophan, and an alteration in tryptophan 5-hydroxytryptamine (5-HT, serotonin) metabolism has been reported in EMS patients...
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Article
Demonstration of specifically sensitized lymphocytes in patients treated with an aqueous mistletoe extract (Viscum album L.)
Lymphocytes of 25 patients treated with an aqueous mistletoe extract (Viscum album L.) for up to 6 months (group 1), up to 2 years (group 2), and more than 2 years (group 3) were examined in 3- and 7-day cultures...
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Article
Anti-mistletoe lectin antibodies are produced in patients during therapy with an aqueous mistletoe extract derived fromViscum album L. and neutralize lectin-induced cytotoxicity in vitro
The humoral response components of an aqueous mistletoe extract (HM) was evaluated in 23 tumor patients who had been treated from 2 months up to 6 years with increasing dosages of HM. IgG antibodies against mi...
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Article
Akute interstitielle Nephritis nach Piperacillin
A 75-year-old woman developed fever, exanthema and nonoliguric renal failure 16 days after the beginning of Piperacillin treatment. Renal biopsy revealed lympho-plasmacellular acute interstitial nephritis (AIN...
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Article
Mitochondrial antigens and autoantibodies: from anti-M1 to anti-M9
The specificity and clinical relevance of nine antimitochondrial antibodies (AMA) — anti-M1 to anti-M9 — are described. All nine AMA types react with antigens which are associated either with inner (M1, M2, M7...
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Article
Indoprofen-induced aplastic anemia in active connective tissue disease detected by drug-specific lymphocyte transformation
In connective tissue diseases, the differentiation of disease-related hematological aberrations from drug-induced cytotoxic or allergic blood-cell dyscrasias is often difficult. In this paper we report on the ...
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Article
Acute interstitial nephritis and non-oliguric renal failure after cefaclor treatment
A case of acute interstitial nephritis (AIN) develo** after cefaclor treatment is reported. Diagnosis was proofed by kidney biopsy and lymphocyte transformation test. The clinical course of the patient with ...
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Article
Myasthenia gravis: Overlap with ‘polyendocrine’ autoimmunity
81 patients with spontaneously acquired myasthenia gravis (MG) were investigated for the presence of autoimmune (AI) diseases and their sera were tested for a range of organ-specific autoantibodies. 77 of the ...
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Article
Autoantibodies and serum inhibition factors (SIF) in patients with myocarditis
54 Patienten mit akuter und chronischer Myokarditis wurden auf Antikörper und Seruminhibitionsfaktoren untersucht. Bei 11 Patienten konnte eine Virusätiologie gesichert werden, bei 17 Patienten bestand der Ver...
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Article
Immunsuppressive Faktoren in Seren und Synovialfüssigkeiten von Patienten mit chronischer Polyarthritis
Serum inhibitory factors (SIF) have been demonstrated in several infectious diseases and autoimmune disorders. Most likely, they are caused by an immune reaction, and their persistence indicates a chronic cour...
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Article
Hepatitis-assoziiertes Antigen (HAA): Klinische und immunologische Bedeutung
Hepatitis-associated antigen (HAA) particles concentrated by isopycnic centrifugation have a modal diameter of approximately 200 Å. HAA resembles some viruses in size, lipid content and density, but contains n...
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Article
Serologische Untersuchungen bei Patienten mit alkoholischer Leberschädigung und ihre differentialdiagnostische Bedeutung
(1) Mitochondrial antibodies were absent in 47 patients with alcoholic liver disease.—(2) Antibodies to smooth muscle and nuclei were more frequently observed in advanced alcoholic cirrhosis than in alcoholic ...
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Article
Immunologische Phänomene bei Leberkrankheiten: Die Bedeutung mitochondrialer Antikörper
Antikörper gegen Zellkerne, glatte Muskulatur und Mitochondrien lassen sich bei der primären biliären Lebercirrhose, der chronisch aktiven Hepatitis und Fällen von kryptogener Lebercirrhose nachweisen.