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Acute interstitial nephritis and non-oliguric renal failure after cefaclor treatment

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Summary

A case of acute interstitial nephritis (AIN) develo** after cefaclor treatment is reported. Diagnosis was proofed by kidney biopsy and lymphocyte transformation test. The clinical course of the patient with non-oliguric renal failure was favourable. Four weeks after discontinuation of cefaclor treatment the renal function was completely restored and remained stable over the ten-month follow-up period. It is concluded that cefaclor can cause hyperallergic AIN and acute renal failure.

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Abbreviations

AIN:

acute interstitial nephritis

Si:

stimulation index

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Authors and Affiliations

  1. Abteilung für allgemeine Innere Medizin und Nephrologie, Freie Universität Berlin, Klinikum Steglitz, Germany

    W. Pommer, H. H. Neumayer & M. Molzahn

  2. Institut für Pathologie, Städtisches Krankenhaus Berlin-Neukölln, Germany

    P. H. Krause

  3. Medizinische Klinik, Eberhard-Karls-Universität, Tübingen

    P. A. Berg

  4. Institut für Pathologie der Universität Basel, Switzerland

    M. J. Mihatsch

Authors
  1. W. Pommer
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  2. P. H. Krause
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  3. P. A. Berg
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  4. H. H. Neumayer
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  5. M. J. Mihatsch
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  6. M. Molzahn
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Pommer, W., Krause, P.H., Berg, P.A. et al. Acute interstitial nephritis and non-oliguric renal failure after cefaclor treatment. Klin Wochenschr 64, 290–293 (1986). https://doi.org/10.1007/BF01711941

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  • DOI: https://doi.org/10.1007/BF01711941

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