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Article
Development of monoclonal antibodies for the sensitive detection and quantification of specific DNA lesions
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Article
After X-irradiation a transient arrest of L929 cells inG 2-phase coincides with a rapid elevation of the level of O6-alkylguanine-DNA alkyltransferase
Following X-irradiation of exponentially growing L929 cells two major phenomena have been observed. First, there was a delay in cell division which can be ascribed to the arrest of cells in theG 2-phase (G 2-bloc...
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Chapter and Conference Paper
Monoclonal Antibodies Directed Against Alkyl-Deoxynucleosides and Cell Type- and Differentiation Stage-Specific Cell Surface Determinants in the Study of Ethylnitrosourea-Induced Carcinogenesis in the Develo** Rat Brain
In this report we describe some properties and applications of two different groups of monoclonal antibodies (Mab) produced in our laboratory for the analysis of molecular and cellular aspects of the process o...
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Article
Immuno-slot-blot: A highly sensitive immunoassay for the quantitation of carcinogen-modified nucleosides in DNA
We have established a highly sensitive immuno-slot-blot (ISB) procedure that can be routinely applied for detection and quantitation of any heat- or alkali-stable structural DNA modification (caused by carcino...