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Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism
Autism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by marked genetic heterogeneity. Recent studies of rare structural and sequence variants have identified hundreds of loci i...
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Article
Putting the landscape into the genomics of trees: approaches for understanding local adaptation and population responses to changing climate
The Forest ecosystem genomics Research: supporTing Transatlantic Cooperation project (FoResTTraC, http://www.foresttrac.eu/) sponsored a workshop in August 2...
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Article
Transforming growth factor α promotes sequential conversion of mature astrocytes into neural progenitors and stem cells
An instability of the mature cell phenotype is thought to participate to the formation of gliomas, primary brain tumors deriving from astrocytes and/or neural stem cells. Transforming growth factor α (TGFα) is an...
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Article
The glycinergic inhibitory synapse
Glycine is one of the most important inhibitory neurotransmitters in the spinal cord and the brainstem, and glycinergic synapses have a well-established role in the regulation of locomotor behavior. Research ...
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Article
Reticulate Evolution:From Bacteria to Philosopher
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Biological Applications of Reticulation Analysis
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Estimation of regionalized phenomena by geostatistical methods: lake acidity on the Canadian Shield
This paper describes a geostatistical technique based on conditional simulations to assess confidence intervals of local estimates of lake pH values on the Canadian Shield. This geostatistical approach has be...
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Article
Denitrification and methane production in sediment of Hamilton Harbour (Canada)
Systematic sampling of 21 sites covering Hamilton Harbour (Lake Ontario, Canada) was carried out during the summer in 1990 and 1991 in order to study how well environmental factors, such as O2, NO ...
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Article
Spatio-temporal variability in fish recruitment to a coral reef (Moorea, French Polynesia)
Spatial and temporal patterns of recruitment of juvenile coral reef fishes were studied on the reefs of the high island of Moorea (Society Archipelago, French Polynesia) during the wet season (October 1988 to ...
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Article
Dopamine affects two voltage-dependent K+ currents of identified rat lactotroph cells
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Proteoglycan biosynthesis by rabbit articular chondrocytes treated withd-penicillamine
Rabbit articular chondrocytes in confluent monolayer cultures were treated withd-Penicillamine (d-Pen) during 3 or 5 days. The [35S]-sulfate incorporation in neosynthesized proteoglycans was not modified byd-Pen ...
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The Neonatal Rat Supraoptic Neurone in Culture:Development of a Model for Control of Peptidergic Secretion
The magnocellular neurones of the hypothalamo-neurohypophysial system have in recent years proved a valuable model in which to examine the complex control of peptidergic secretion, in particular oxytocin and v...
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Article
Metric and Euclidean properties of dissimilarity coefficients
We assemble here properties of certain dissimilarity coefficients and are specially concerned with their metric and Euclidean status. No attempt is made to be exhaustive as far as coefficients are concerned, b...
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Article
Facteurs responsables de la distribution des gastéropodes dulcicoles dans le fleuve Saint-Laurent
A study of the freshwater gastropods in the Saint Lawrence river near Montreal was undertaken to characterize the populations living in the benthos and on the vegetation, and to define the effects of a deterio...
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99mTc labeled red blood cells versus γ-phlebography in diagnosis of deep vein thrombosis