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  1. No Access

    Article

    Family-based association study of serotonergic candidate genes and attention-deficit/hyperactivity disorder in a German sample

    Alterations in the serotonergic pathway have been implicated in the pathogenesis of attention-deficit/hyperactivity disorder (ADHD). The aim of this study was to investigate seven genetic variants in three gen...

    P. Heiser, A. Dempfle, S. Friedel, K. Konrad, A. Hinney… in Journal of Neural Transmission (2007)

  2. No Access

    Article

    Weight gain associated with clozapine, olanzapine and risperidone in children and adolescents

    The study was aimed at the evaluation of weight gain associated with atypical antipsychotics and its clinical risk factors in children and adolescents. Weight and body mass index (BMI) of initially hospitalise...

    C. Fleischhaker, P. Heiser, K. Hennighausen… in Journal of Neural Transmission (2007)

  3. No Access

    Article

    A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs

    Three groups have previously performed genome scans in attention-deficit/hyperactivity disorder (ADHD); linkage to chromosome 5p13 was detected in all of the respective studies. In the current study, we perfor...

    J Hebebrand, A Dempfle, K Saar, H Thiele, B Herpertz-Dahlmann… in Molecular Psychiatry (2006)

  4. No Access

    Article

    Objective measurement of hyperactivity, impulsivity, and inattention in children with hyperkinetic disorders before and after treatment with methylphenidate

    The purpose of this study was to investigate whether values of the respective parameters of the OPTAx test dependently differ due to the medication with methylphenidate (MPH) in children with hyperkinetic diso...

    P. Heiser, J. Frey, J. Smidt, C. Sommerlad… in European Child & Adolescent Psychiatry (2004)

  5. No Access

    Article

    Effect of lazaroid pretreatment on dopamine-induced impairment of the rat nigrostriatal system

    Oxidative stress induced by enhanced catecholamine metabolism may subsequently cause damages to the nervous system. We used in vivo-pulse voltammetry to study an enhanced brain dopamine (metabolism) induced e...

    H.-W. Clement, C. Grote, P. Heiser, W. Wesemann in Journal of Neural Transmission (2002)

  6. No Access

    Chapter and Conference Paper

    Regulation serotonerger Parameter durch Clozapin und seine Metaboliten in hippokampalen HT22-Zellen

    Das atypische Neuroleptikum Clozapin induziert Veränderungen im serotonergen System. Es hat eine hohe Affinität zum 5-HT2A-Rezeptor und führt zu einer Erhöhung des Serotonin-(5-HT-)Spiegels (Schulz et al. 1997; R...

    P. Heiser, H. Remschmidt, J.-C. Krieg, H. Vedder in Leponex (2001)

  7. No Access

    Article

    White blood cells and cortisol after sleep deprivation and recovery sleep in humans

    Sleep deprivation (SD) has enriched our treatment programme for major depression. SD has been demonstrated to modify different host defence activities. There is some evidence that there are reciprocal relatio...

    P. Heiser, B. Dickhaus, W. Schreiber… in European Archives of Psychiatry and Clinic… (2000)

  8. No Access

    Article

    Platelet serotonin and interleukin-1β after sleep deprivation and recovery sleep in humans

    Sleep deprivation (SD) represents a well-established therapy for major depression. Recent findings suggest that the antidepressive effects of sleep deprivation are mediated at least in part by pro-serotoninerg...

    P. Heiser, B. Dickhaus, C. Opper, W. Schreiber… in Journal of Neural Transmission (1997)

  9. Article

    Colour Photography of the Aurora

    STØRMER1 refers to the difficulty of photographing the aurora in colour, and states that satisfactory results have not been obtained, except for arcs and more quiet forms. However, with a colour film now availabl...

    B. P. SANDFORD, P. HEISER in Nature (1959)

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