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  1. Article

    Open Access

    The psoriasis-protective TYK2 I684S variant impairs IL-12 stimulated pSTAT4 response in skin-homing CD4+ and CD8+ memory T-cells

    Tyrosine kinase 2 (TYK2) belongs to the Janus kinase (JAK) family of tyrosine kinases, which transmit signals from activated cytokine receptors. GWAS have consistently implicated TYK2 in psoriasis susceptibility....

    C. Enerbäck, C. Sandin, S. Lambert, M. Zawistowski, P. E. Stuart… in Scientific Reports (2018)

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    Article

    The EGF receptor ligand amphiregulin controls cell division via FoxM1

    Epidermal growth factor receptor (EGFR) is central to epithelial cell physiology, and deregulated EGFR signaling has an important role in a variety of human carcinomas. Here we show that silencing of the EGF-r...

    S W Stoll, P E Stuart, W R Swindell, L C Tsoi, B Li, A Gandarillas, S Lambert… in Oncogene (2016)