![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessTargeted next-generation sequencing of circulating free DNA enables non-invasive tumor detection in myxoid liposarcomas
-
Article
Open AccessATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival
The ATP-gated receptor P2X7 is expressed in multiple malignant tumours including neuroblastoma, melanoma, prostate, lung and breast. P2X7 has a significant role in mediating diverse cell responses, which upon dys...
-
Article
Zirkulierende Tumorzellen beim Pankreaskarzinom
Das duktale Adenokarzinom des Pankreas (PDAC) ist eine aggressive Krebserkrankung mit einer oft infausten Prognose. Charakteristisch für PDAC sind KRAS-Mutationen in Codon 12/13. Bei einigen Karzinompatienten las...
-
Article
Das intrahepatische Cholangiokarzinom
Die Inzidenz intrahepatischer Cholangiokarzinome (ICC) nimmt weltweit zu. Eine Resektion ist die einzige kurative Behandlungsmöglichkeit.
-
Article
Open AccessQuantitative proteomic analysis of formalin–fixed, paraffin–embedded clear cell renal cell carcinoma tissue using stable isotopic dimethylation of primary amines
Formalin-fixed, paraffin-embedded (FFPE) tissues represent the most abundant resource of archived human specimens in pathology. Such tissue specimens are emerging as a highly valuable resource for translationa...