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Article
A missense mutation in the human melanocortin-4 receptor gene in relation to abdominal obesity and salivary cortisol
The melanocortin-4 receptor (MC4-R) regulates food intake and possibly energy expenditure, and the inactivation of the MC4-R by gene targeting results in obesity, a phenotype strongly associated with Type II ...
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Article
Psychosocial and socio-economic factors in women and their relationship to obesity and regional body fat distribution
BACKGROUND: Abdominal obesity, as well as psychosocial and socio-economic handicaps are risk factors for serious, prevalent diseases. Connections between these variables have been found in men.
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Article
Rapid formation of capillary endothelial cells in rat skeletal muscle after exposure to insulin
Research has suggested a role for insulin delivery through capillaries in muscle in the regulation of insulin sensitivity. Therefore, the formation and turn-over of capillary endothelial cells in muscle were s...
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Article
Risk factors for Type 2 (non-insulin-dependent) diabetes mellitus. Thirteen and one-half years of follow-up of the participants in a study of Swedish men born in 1913
This report presents data on antecedents of Type 2 (non-insulin-dependent) diabetes mellitus in a homogeneous sample of randomly selected 54-year-old men from an urban Swedish population with a diabetes incide...
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Article
The effects of physical training on insulin secretion and effectiveness and on glucose metabolism in obesity and Type 2 (non-insulin-dependent) diabetes mellitus
Obese subjects with normal glucose tolerance (n=55), and, in another study, a group of patients with Type 2 (non-insulin-dependent) diabetes (n=33), and controls (n=13) matched for body weight and age but with no...
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Article
Influence of phenformin and metformin on exercise induced lactataemia in patients with diabetes mellitus
The effect of long-term treatment with phenformin and metformin respectively on blood lactate concentrations in relation to submaximal muscular exercise has been examined in 21 maturity-onset diabetics, using ...
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Article
Influence of cell size on the effects of insulin and noradrenaline on human adipose tissue
In the present study dose-response relationships of the effects of noradrenaline and insulin on fat cells of different sizes were performed. Adipose cells larger than 100 μm were more responsive (expressed as ...
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Article
Adipose tissue cellularity in relation to metabolism in juvenile onset diabetes mellitus
Adipose tissue cellularity was determined by a microscopic method in 18 men suffering from insulin dependent, juvenile diabetes mellitus for several years. These results were set in relation to the degree of c...
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Article
The effect of maternal diabetes on adipose tissue cellularity in man and rat
It is well recognised that the newborn of diabetic mothers may be overweight and obese, presumably due to excessive glucose and insulin levels in the fetus. Since recent evidence indicates that the number of f...
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Article
Insulin secretion in obesity after exercise
Blood glucose and plasma insulin during glucose loads were measured in nine obese patients before and twice the days after a submaximal work of long duration. All subjects showed lower plasma insulin values th...
