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  1. Article

    Open Access

    Real-world evidence of ocrelizumab-treated relapsing multiple sclerosis cohort shows changes in progression independent of relapse activity mirroring phase 3 trials

    Ocrelizumab is a B cell-depleting drug widely used in relapsing–remitting multiple sclerosis (RRMS) and primary-progressive MS. In RRMS, it is becoming increasingly apparent that accumulation of disability not...

    J. Ingwersen, L. Masanneck, M. Pawlitzki, S. Samadzadeh, M. Weise in Scientific Reports (2023)

  2. Article

    Open Access

    Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile

    Extracellular nucleotides act as danger signals that orchestrate inflammation by purinergic receptor activation. The expression pattern of different purinergic receptors may correlate with a pro- or anti-infla...

    J. Merz, A. Nettesheim, S. von Garlen, P. Albrecht, B. S. Saller in Purinergic Signalling (2021)

  3. No Access

    Article

    Asylbewerber und ihre Versorgungssituation

    Die medizinische Versorgung von geflüchteten Menschen ist in Deutschland gesetzlich stark reguliert. Die regional sehr unterschiedliche Umsetzung stellt derzeit aber eine große Herausforderung dar. Die spezifi...

    Dr. P. Klein, P. Albrecht in Monatsschrift Kinderheilkunde (2017)

  4. Article

    BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival

    The endoplasmic reticulum (ER) serves as the major intracellular Ca2+ store and has a role in the synthesis and folding of proteins. BAX (BCL2-associated X protein) inhibitor-1 (BI-1) is a Ca2+ leak channel also ...

    D Lisak, T Schacht, A Gawlitza, P Albrecht, O Aktas, B Koop in Cell Death & Differentiation (2016)

  5. No Access

    Chapter

    Gastroesophageal Reflux Disease in Children with Interstitial Lung Disease

    Gastroesophageal reflux disease is common in adult patients with interstitial lung disease. However, no data currently exist regarding the prevalence and characteristics of the disease in pediatric patients wi...

    M. A. Dziekiewicz, K. Karolewska-Bochenek in Prospect in Pediatric Diseases Medicine (2016)

  6. Article

    Open Access

    Controlling a VRE cluster on a surgical ward

    C Bandiera-Clerc, C Coccault-Duverger in Antimicrobial Resistance and Infection Con… (2015)

  7. No Access

    Chapter and Conference Paper

    Evaluation of Laryngopharyngeal Reflux in Pediatric Patients with Asthma Using a New Technique of Pharyngeal pH-Monitoring

    There is a debate about the association between asthma and gastroesophageal and/or laryngopharyngeal reflux (LPR). Pharyngeal pH-monitoring is a new technique that allows a physician to assess whether reflux p...

    A. Banaszkiewicz, L. Dembinski in Respiratory Regulation - Clinical Advances (2013)

  8. Article

    Open Access

    The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress

    The mouse hippocampal cell line HT22 is an excellent model for studying the consequences of endogenous oxidative stress. Addition of extracellular glutamate depletes the cells of glutathione (GSH) by blocking ...

    N Henke, P Albrecht, I Bouchachia, M Ryazantseva, K Knoll in Cell Death & Disease (2013)

  9. No Access

    Article

    Indirect population impact of universal PCV7 vaccination of children in a 2 + 1 schedule on the incidence of pneumonia morbidity in Kielce, Poland

    The aim of this study was an analysis of the population effects of a seven-valent pneumococcal conjugate vaccine (PCV7) on pneumonia incidence rates in the 5-year follow-up period after the introduction in 200...

    M. Patrzalek, P. Gorynski, P. Albrecht in European Journal of Clinical Microbiology … (2012)

  10. Article

    Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression

    Selecting neuronal cell lines for resistance against oxidative stress might recapitulate some adaptive processes in neurodegenerative diseases where oxidative stress is involved like Parkinson's disease. We re...

    J Lewerenz, H Sato, P Albrecht, N Henke, R Noack, A Methner in Cell Death & Differentiation (2012)

  11. No Access

    Article

    POEMS-Syndrom

    Das POEMS-Syndrom ist eine seltene paraneoplastische Erkrankung, die mit einer Polyneuropathie, Organomegalie, Endokrinopathie, monoklonalen Plasmazellerkrankung und Haut („Skin“)-Veränderungen einhergeht. Erhöht...

    S.A. Braun, P. Albrecht, A. Methner, Dr. S. Hanneken in Der Hautarzt (2011)

  12. No Access

    Article

    Significant decline in pneumonia admission rate after the introduction of routine 2+1 dose schedule heptavalent pneumococcal conjugate vaccine (PCV7) in children under 5 years of age in Kielce, Poland

    This study was performed to estimate the effect of heptavalent pneumococcal conjugate vaccine (PCV7) on the pneumonia admission rate in children younger than 5 years of age, after the introduction of routine 2...

    M. Patrzałek, P. Albrecht, M. Sobczynski in European Journal of Clinical Microbiology … (2010)

  13. Article

    Open Access

    Free caspase activity in CSF of patients with dementia

    P. Albrecht, M. Schmitz, M. Otto, B. Hemmer, I. Zerr, H.-P. Hartung in Journal of Neurology (2009)

  14. No Access

    Article

    Invasive pneumococcal disease in children up to 5 years of age in Poland

    P. Grzesiowski, A. Skoczynska, P. Albrecht in European Journal of Clinical Microbiology … (2008)

  15. No Access

    Article

    Optical coherence tomography measures axonal loss in multiple sclerosis independently of optic neuritis

    P. Albrecht, R. Fröhlich, H.-P. Hartung, B. C. Kieseier in Journal of Neurology (2007)

  16. No Access

    Chapter and Conference Paper

    NACA0012 wing with rounded tip

    This chapter describes the common effort of UMIST, EADS-CASA, ALENIA and TUB to compute the steady vortex evolving at the round tip of a wing at 10° angle of attack. Results for different numerical grids obtai...

    P. Albrecht, D. Wu, A. Martin, U. Bunge in FLOMANIA — A European Initiative on Flow P… (2006)

  17. No Access

    Article

    Temperature-Induced Change of Variant Surface Antigen Expression in ParameciumInvolves Antigen Release into the Culture Medium with Considerable Delay betweenTranscription and Surface Expression

    We analyzed temperature-induced changes of variant surface antigen (vsAg) expression in Paramecium primaurelia, using immuno-techniques and mRNA determinations. Upon a 23°C to 33°C shift, the old vsAg, type 156G,...

    M. Momayezi, P. Albrecht, H. Plattner, H. J. Schmidt in The Journal of Membrane Biology (2004)

  18. No Access

    Article

    Analysis of optical crosstalk within optoelectronic integrated circuits including lasers and photodetectors

    Optical crosstalk from a 1.3 μm laser to a 1.55 μm photodiode on a single InP substrate, and its suppression within 1.3 μm/1.5 μm Y-junction transceiver OEICs, has been analyzed experimentally. The results ind...

    H. Heidrich, R. Kaiser, P. Albrecht, S. Fidorra, M. Hamacher in Applied Physics B (2001)

  19. No Access

    Article

    Extraction of bound porphyrins from sulphur-rich sediments and their use for reconstruction of palaeoenvironments

    PORPHYRINS, which are present in most sediments and crude oils, represent the 'molecular fossils' of compounds such as chlorophylls, bacteriochlorophylls and haems in the organisms from which the organic mater...

    P. Schaeffer, R. Ocampo, H. J. Callot, P. Albrecht in Nature (1993)

  20. No Access

    Article

    Structural evidence for heme fossils in Messel oil shale (FRG)

    C. Bauder, R. Ocampo, H. J. Callot, P. Albrecht in Naturwissenschaften (1990)

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