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    Open Access

    Distinctive roles of translesion polymerases DinB1 and DnaE2 in diversification of the mycobacterial genome through substitution and frameshift mutagenesis

    Antibiotic resistance of Mycobacterium tuberculosis is exclusively a consequence of chromosomal mutations. Translesion synthesis (TLS) is a widely conserved mechanism of DNA damage tolerance and mutagenesis, exec...

    Pierre Dupuy, Shreya Ghosh, Oyindamola Adefisayo, John Buglino in Nature Communications (2022)