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Article
Open AccessORPHAcodes use for the coding of rare diseases: comparison of the accuracy and cross country comparability
Estimates of rare disease (RD) population impact in terms of number of affected patients and accurate disease definition is hampered by their under-representation in current coding systems. This study tested t...
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Article
Open AccessDifferences in breast cancer-risk factors between screen-detected and non-screen-detected cases (MCC-Spain study)
The variation in breast cancer (BC)-risk factor associations between screen-detected (SD) and non-screen-detected (NSD) tumors has been poorly studied, despite the interest of this aspect in risk assessment an...
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Article
Open AccessThe interoperability between the Spanish version of the International Classification of Diseases and ORPHAcodes: towards better identification of rare diseases
Rare diseases present a wide spectrum of clinical manifestations and severity levels and are often poorly known and underrepresented, making them difficult to classify. Diagnoses are usually coded using the In...
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Article
Open AccessTrends in socioeconomic inequalities in preventable mortality in urban areas of 33 Spanish cities, 1996–2007 (MEDEA project)
Preventable mortality is a good indicator of possible problems to be investigated in the primary prevention chain, making it also a useful tool with which to evaluate health policies particularly public health...
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Article
Open AccessCare provided and care setting transitions in the last three months of life of cancer patients: a nationwide monitoring study in four European countries
This is an international study across four European countries (Belgium[BE], the Netherlands[NL], Italy[IT] and Spain[ES]) between 2009 and 2011, describing and comparing care and care setting transitions provi...
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Article
Open AccessNational rare diseases registry in Spain: pilot study of the Spanish Rare Diseases Registries Research Network (SpainRDR)
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Article
Open AccessTrends in socioeconomic inequalities in amenable mortality in urban areas of Spanish cities, 1996–2007
While research continues into indicators such as preventable and amenable mortality in order to evaluate quality, access, and equity in the healthcare, it is also necessary to continue identifying the areas of...
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Article
Inequalities in Perinatal Mortality Rates Among Immigrant and Native Population in Spain, 2005–2008
We compared perinatal mortality rates (PMRs) and the risk from certain causes among immigrant and native population in the Valencian Community (Spain). Using data from the Perinatal Mortality Registry, crude a...
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Article
Open AccessNationwide continuous monitoring of end-of-life care via representative networks of general practitioners in Europe
Although end-of-life care has become an issue of great clinical and public health concern in Europe and beyond, we lack population-based nationwide data that monitor and compare the circumstances of dying and ...
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Article
Open AccessDo socioeconomic inequalities in mortality vary between different Spanish cities? a pooled cross-sectional analysis
The relationship between deprivation and mortality in urban settings is well established. This relationship has been found for several causes of death in Spanish cities in independent analyses (the MEDEA proje...
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Article
A very rare cancer in Down syndrome: medulloblastoma. Epidemiological data from 13 countries
Persons with Down syndrome (DS) uniquely have an increased frequency of leukemias but a decreased total frequency of solid tumors. The distribution and frequency of specific types of brain tumors have never be...
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Article
Open AccessSpatio-temporal evolution of female lung cancer mortality in a region of Spain, is it worth taking migration into account?
The Comunitat Valenciana (CV) is a tourist region on the Mediterranean coast of Spain with a high rate of retirement migration. Lung cancer in women is the cancer mortality cause that has increased most in the...
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Source Detection in an Outbreak of Legionnaire’s Disease
Spatial statistics have broadly been applied, developed and demanded from the field of epidemiology. The point process theory is an appropriate framework to analyse the spatial variation of risk of disease fro...
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Article
Regional Variability in Population Acute Myocardial Infarction Cumulative Incidence and Mortality Rates in Spain 1997 and 1998
Background: Myocardial infarction (MI) incidence and mortality display a high geographic variation. Aims: The objective of the present study was to analyze MI mortality, cumulative incidence rate variability in ...
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Geographical Distribution of Cardiovascular Mortality in Comunidad Valenciana (Spain)
Comunidad Valenciana is one of the seventeen autonomous regions into which Spain is divided. It is located on the east coast of Spain, next to the Mediterranean sea, with an area of 23,255 km2 and with 4,009,329 ...