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Open AccessClassifying Neuronal Cell Types Based on Shared Electrophysiological Information from Humans and Mice
The brain is an intricate system that controls a variety of functions. It consists of a vast number of cells that exhibit diverse characteristics. To understand brain function in health and disease, it is cruc...
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Article
Open AccessA streptavidin–biotin system combined with magnetic actuators for remote neuronal guidance
The ability to control neuronal mobility and organization is of great importance in develo** neuronal interfaces and novel therapeutic approaches. An emerging promising method is the manipulation of neuronal...
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Engineering Oriented Scaffolds for Directing Neuronal Regeneration
Following nervous system injuries, such as peripheral or spinal cord injuries, severed nerves must regenerate to reinnervate tissues and restore lost-functionality. In many peripheral nerve injuries surgical i...
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Article
Axonal Tree Morphology and Signal Propagation Dynamics Improve Interneuron Classification
Neurons are diverse and can be differentiated by their morphological, electrophysiological, and molecular properties. Current morphology-based classification approaches largely rely on the dendritic tree struc...
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Article
Open AccessLarge-scale acoustic-driven neuronal patterning and directed outgrowth
Acoustic manipulation is an emerging non-invasive method enabling precise spatial control of cells in their native environment. Applying this method for organizing neurons is invaluable for neural tissue engin...
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Article
Open AccessBranching morphology determines signal propagation dynamics in neurons
Computational modeling of signal propagation in neurons is critical to our understanding of basic principles underlying brain organization and activity. Exploring these models is used to address basic neurosci...
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Article
Open Access26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3
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Effect of different densities of silver nanoparticles on neuronal growth
Nerve regeneration has become a subject of great interest, and much effort is devoted to the design and manufacturing of effective biomaterials. In this paper, we report the capability of surfaces coated with ...
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Article
Open AccessIron oxide nanoparticles for neuronal cell applications: uptake study and magnetic manipulations
The ability to direct and manipulate neuronal cells has important potential in therapeutics and neural network studies. An emerging approach for remotely guiding cells is by incorporating magnetic nanoparticle...
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Article
Open AccessDe novo transcriptome assembly databases for the central nervous system of the medicinal leech
The study of non-model organisms stands to benefit greatly from genetic and genomic data. For a better understanding of the molecular mechanisms driving neuronal development, and to characterize the entire leech
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Article
Open AccessBombarding Cancer: Biolistic Delivery of therapeutics using Porous Si Carriers
A new paradigm for an effective delivery of therapeutics into cancer cells is presented. Degradable porous silicon carriers, which are tailored to carry and release a model anti-cancer drug, are biolistically ...
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Open AccessNeuronal morphology as an instrument for information coding: studying the influence of axonal radius and branching points
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Interactions of neurons with topographic nano cues affect branching morphology mimicking neuron–neuron interactions
We study the effect of topographic nano-cues on neuronal growth-morphology using invertebrate neurons in culture. We use photolithography to fabricate substrates with repeatable line-pattern ridges of nano-sca...