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Chapter
Coalescent Models of Demographic History: Application to Plant Domestication
A detailed understanding of the origins of domesticated species is important for many disciplines. Recent advances in this field have been made with the use of genome-wide polymorphisms and improved statistica...
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Article
Open AccessDetailed histological analysis of a thrombectomy-resistant ischemic stroke thrombus: a case report
Mechanical removal of a thrombus by thrombectomy can be quite challenging. For reasons that are not fully understood, some thrombi require multiple passes to achieve successful recanalization, whereas other th...
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Article
Open AccessFactor analysis of ancient population genomic samples
The recent years have seen a growing number of studies investigating evolutionary questions using ancient DNA. To address these questions, one of the most frequently-used method is principal component analysis...
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Article
Open AccessGenome Wide Association Study Pinpoints Key Agronomic QTLs in African Rice Oryza glaberrima
African rice, Oryza glaberrima, is an invaluable resource for rice cultivation and for the improvement of biotic and abiotic resistance properties. Since its domestication in the inner Niger delta ca. 2500 years ...
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Article
A western Sahara centre of domestication inferred from pearl millet genomes
There have been intense debates over the geographic origin of African crops and agriculture. Here, we used whole-genome sequencing data to infer the domestication origin of pearl millet (Cenchrus americanus). Our...
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Article
Open AccessMolecular basis of African yam domestication: analyses of selection point to root development, starch biosynthesis, and photosynthesis related genes
After cereals, root and tuber crops are the main source of starch in the human diet. Starch biosynthesis was certainly a significant target for selection during the domestication of these crops. But domesticat...
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Article
Open AccessNew insights into HCV replication in original cells from Aedes mosquitoes
The existing literature about HCV association with, and replication in mosquitoes is extremely poor. To fill this gap, we performed cellular investigations aimed at exploring (i) the capacity of HCV E1E2 glyco...
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Article
Probabilistic analysis of a genealogical model of animal group patterns
Many social animals live in stable groups, and it has been argued that kinship plays a major role in their group formation process. In this study we present the mathematical analysis of a recent model which us...
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Article
Non-linear regression models for Approximate Bayesian Computation
Approximate Bayesian inference on the basis of summary statistics is well-suited to complex problems for which the likelihood is either mathematically or computationally intractable. However the methods that u...
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Article
Is digital substraction angiography still needed for the follow-up of intracranial aneurysms treated by embolisation with detachable coils?
Follow-up of intracranial aneurysms treated by embolisation with detachable coils is mandatory to detect a possible recanalisation. The aim of this study was to compare contrast-enhanced magnetic resonance ang...
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Chapter and Conference Paper
Convergence Analysis of Evolution Strategies with Random Numbers of Offspring
Hitting times of the global optimum for evolutionary algorithms are usually available for simple unimodal problems or for simplified algorithms. In discrete problems, the number of results that relate the conv...
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Article
Open AccessA statistical approach to estimating the strength of cell-cell interactions under the differential adhesion hypothesis
The Differential Adhesion Hypothesis (DAH) is a theory of the organization of cells within a tissue which has been validated by several biological experiments and tested against several alternative computation...
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Article
Sharp Asymptotics for Fixation Times in Stochastic Population Genetics Models at Low Mutation Probabilities
This article describes new models in population genetics that extend the neutral Wright–Fisher model by including strong selection and mutation. Fixation times are studied in the limit of small mutation probab...
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Chapter and Conference Paper
Niching in Monte Carlo Filtering Algorithms
Nonlinear multimodal filtering problems are usually addressed via Monte Carlo algorithms. These algorithms involve sampling procedures that are similar to proportional selection in genetic algorithms, and that...
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Chapter and Conference Paper
Large Deviations, Evolutionary Computation and Comparisons of Algorithms
This paper summarizes large deviations results for Markov chains with exponential transitions, and discusses their applications in comparing stochastic optimization algorithms. In the second half, two specific...
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Chapter and Conference Paper
Parameters Estimation in the Diffusion Model for Multidimensional Neural Data
The aim of this study is to propose a new model to analyze multisite spatiotemporal neuronal data, and to provide a new method to estimate the parameters of the model from real data. This model is based on the...
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Article
Pulmonary and mediastinal lesions in children with Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is an uncommon group of disorders affecting mainly children and young adults. In children, pulmonary involvement occurs mostly in the disseminated forms; isolated pulmonary...
