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Chapter and Conference Paper
Psychological Aspects of Face-To-Face Versus Computer-Mediated Interpersonal Communication: An Integrative Review
Computer mediated (CM) communication has become pervasive in everyday lives of people in many societies, especially during and after the COVID pandemics, which has had profound effects on different aspects of ...
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Article
Open AccessNicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder
Oxytocin (OT) is a critical molecule for social recognition and memory that mediates social and emotional behaviours. In addition, OT acts as an anxiolytic factor and is released during stress. Based on the ac...
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Chapter
Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus
Oxytocin (OT) is a critical molecule for social recognition that mediates social memory and emotional behaviors. OT is known to be released during stress and acts as an anxiolytic factor. Recent studies reveal...
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Article
Open AccessVascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal bonding behaviours. Mice lacking secreted oxcytocin (Oxt−/−, Cd38−/−) or its receptor (Oxtr−/−) fail to nurture. N...
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Article
Cyclic ADP-ribose as an endogenous inhibitor of the mTOR pathway downstream of dopamine receptors in the mouse striatum
The role of cyclic ADP-ribose (cADPR) as a second messenger and modulator of the mTOR pathway downstream of dopamine (DA) receptors and/or CD38 was re-examined in the mouse. ADP-ribosyl activity was low in the...
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Article
Open AccessIntestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice
Plasma oxytocin (OT) originates from secretion from the pituitary gland into the circulation and from absorption of OT in mother’s milk into the blood via intestinal permeability. However, the molecular mechan...
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Article
Open AccessAn immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator
Recent rodent and human studies provide evidence in support of the fact that CD157, well known as bone marrow stromal cell antigen-1 (BST-1) and a risk factor in Parkinson’s disease, also meaningfully acts in ...
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Article
Open AccessCD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice
Mammalian sires participate in infant care. We previously demonstrated that sires of a strain of nonmonogamous laboratory mice initiate parental retrieval behavior in response to olfactory and auditory signals...
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Article
Open AccessDisplays of paternal mouse pup retrieval following communicative interaction with maternal mates
Compared with the knowledge of maternal care, much less is known about the factors required for paternal parental care. Here we report that new sires of laboratory mice, though not spontaneously parental, can ...
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Article
CD38 is critical for social behaviour by regulating oxytocin secretion
CD38, a transmembrane glycoprotein with ADP-ribosyl cyclase activity, catalyses the formation of Ca2+ signalling molecules, but its role in the neuroendocrine system is unknown. Here we show that adult CD38 knock...
