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  1. No Access

    Article

    The Senolytic Drug JQ1 Removes Senescent Cells via Ferroptosis

    Ferroptosis is an iron-dependent, non-apoptotic programmed cell death. Cellular senescence contributes to aging and various age-related diseases through the expression of a senescence-associated secretory phen...

    Seokhyeong Go, Mikyung Kang, Sung Pil Kwon… in Tissue Engineering and Regenerative Medici… (2021)

  2. Article

    Open Access

    Plasma dilution improves cognition and attenuates neuroinflammation in old mice

    Our recent study has established that young blood factors are not causal, nor necessary, for the systemic rejuvenation of mammalian tissues. Instead, a procedure referred to as neutral blood exchange (NBE) tha...

    Melod Mehdipour, Taha Mehdipour, Colin M. Skinner, Nathan Wong, Chao Liu… in GeroScience (2021)

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    Article

    Quantification of temporal changes in 3D osteoclastic resorption pit using confocal laser scanning microscopy

    Osteoclasts, cells responsible for bone resorption, generate 3D resorption pits by attaching to the bone surface and excavating the underneath bone matrix. Changes in trabecular bone microstructure due to thes...

    Ok Hee Jeon, Su Ho Jeong, Yeong-Min Yoo… in Tissue Engineering and Regenerative Medici… (2012)

  4. No Access

    Article

    Primary Cilia-Mediated Osteogenic Response to Fluid Flow Occurs via Increases in Focal Adhesion and Akt Signaling Pathway in MC3T3-E1 Osteoblastic Cells

    Fluid flow is an important anabolic mechanical signal that results in the upregulation of osteogenic responses in bone cells. Primary cilium may be responsible for the sensing of mechanical signals and convert...

    Ok Hee Jeon, Yeong-Min Yoo, Kyung Hwan Kim… in Cellular and Molecular Bioengineering (2011)