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  1. No Access

    Article

    Cryo-EM Structure of Bovine Chaperonin TRiC/CCT in Open Conformation

    In this work, conditions were selected for obtaining a sample of eukaryotic chaperonin TRiC suitable for studying by cryo-electron microscopy. Using the method of differential scanning (time-resolved) fluorime...

    T. B. Stanishneva-Konovalova, E. B. Pichkur… in Moscow University Biological Sciences Bull… (2023)

  2. No Access

    Article

    Investigation of the Effect of a Single-Stranded Break on the Mechanical Parameters of DNA by Molecular Dynamics Method

    Early detection and repair of damaged DNA is important for cell functioning and survival. The recently proposed mechanism of intranucleosomal loop formation suggests the relaxation of DNA supercoiling accumula...

    O. I. Volokh, G. A. Armeev, E. S. Trifonova… in Moscow University Biological Sciences Bull… (2020)

  3. No Access

    Article

    Study of RNA polymerase transcription through nucleosome using the cryo-electron microscopy approach

    A promising and reliable method for the analysis of macromolecule structures is capturing images using cryo-electron transmission microscopy and consequently performing three-dimensional reconstructions. In th...

    O. I. Volokh, F. K. Hsieh, M. G. Karlova… in Moscow University Biological Sciences Bull… (2016)