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  1. No Access

    Article

    In situ depletion of CD4+ T cells in human skin by Zanolimumab

    CD4+ T cells, in activated or malignant form, are involved in a number of diseases including inflammatory skin diseases such as psoriasis, and T cell lymphomas such as the majority of cutaneous T cell lymphomas (...

    L. S. Villadsen, L. Skov, T. N. Dam… in Archives of Dermatological Research (2007)

  2. No Access

    Article

    Association of TNFA gene polymorphism at position –308 with susceptibility to irritant contact dermatitis

     Mechanisms underlying susceptibility to skin irritants are not clearly understood. Cytokines play a key role in inflammation, and functional polymorphisms in cytokine genes may affect responses to irritants. ...

    M. H. Allen, S. H. Wakelin, D. Holloway, S. Lisby, O. Baadsgaard… in Immunogenetics (2000)

  3. No Access

    Article

    Nickel-induced activation of T cells in individuals with negative patch test to nickel sulphate

    S. Lisby, L. H. Hansen, L. Skov, T. Menné… in Archives of Dermatological Research (1999)

  4. No Access

    Article

    Lesional alopecia areata T lymphocytes downregulate epithelial cell proliferation

    Alopecia areata is characterized by peribulbar infiltration by activated T cells. The function of these T cells in the pathogenesis is unknown. To elucidate the potential role of lesional T cells...

    Christina Thein, Poul Strange, Erik René Hansen… in Archives of Dermatological Research (1997)

  5. No Access

    Article

    Psoriatic skin reveals the in vivo presence of an epidermal IL-1 inhibitor

    Production of inhibitor(s) of IL-1 activity can be induced in keratinocytes by exposure to UVB. We describe in this study the characterization of an endogenous constitutively expressed IL-1 inhibitor which is ...

    N.-I. Kim, K. D. Cooper M.D., G. J. Fisher… in Archives of Dermatological Research (1992)

  6. No Access

    Article

    Effects of Sandimmun on T lymphocyte and dendritic cell subpopulations in psoriasis

    B. S. Baker, L. Fry, A. V. Powles, A. K. Gupta… in Archives of Dermatological Research (1990)

  7. No Access

    Article

    Lymphocytes and macrophages of the epidermis and dermis in lesional psoriatic skin, but not epidermal Langerhans cells, are depleted by treatment with cyclosporin A

    Since cyclosporin A (CsA) is an immuno-suppressive agent, its beneficial effect in psoriasis suggests that immune cells may play a role in the pathogenesis and resolution of psoriasis. To determine early effec...

    A. K. Gupta, O. Baadsgaard, C. N. Ellis… in Archives of Dermatological Research (1989)

  8. No Access

    Article

    Reduction of the number of immunocompetent cells in the acute stage of herpes zoster

    Circulating and in situ mononuclear cell subsets were phenotypically characterized during both the acure and convalescent phase of herpes zoster infections in 14 patients. In peripheral blood a significant red...

    O. Baadsgaard, R. Lindskov, C. Geisler in Archives of Dermatological Research (1987)

  9. No Access

    Article

    Lymphocyte subsets in patients with compositae oleoresin dermatitis and increased UVA sensitivity during treatment with azathioprine

    Four patients with severe contact dermatitis resulting from compositae oleoresin were found to have increased sensitivity to ultraviolet light. All showed a clear reduction of Leu-3a-positive lymphocytes (T he...

    O. Baadsgaard, C. Geisler, T. Plesner… in Archives of Dermatological Research (1985)