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    Article

    Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

    Sjaak Philipsen and colleagues report that haploinsufficiency for KLF1 causes hereditary persistence of fetal hemoglobin in a large Maltese family. They further show that KLF1 is a key activator of BCL11A, whi...

    Joseph Borg, Petros Papadopoulos, Marianthi Georgitsi, Laura Gutiérrez… in Nature Genetics (2010)

  2. Article

    Open Access

    Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors

    Both tissue-specific and ubiquitously expressed transcription factors, such as Sp-family members, are required for correct development. However, the molecular details of how ubiquitous factors are involved in ...

    Jane Gilmour, Leigh O’Connor, Christopher P. Middleton… in Epigenetics & Chromatin (2019)

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