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  1. Article

    Open Access

    Pharmacokinetic–pharmacodynamic modelling of the hypoglycaemic effect of pulsatile administration of human insulin in rats

    The relationship between the plasma insulin (INS) concentration–time course and plasma glucose concentration–time course during and after pulsatile INS administration to rats was characterized using a pharmaco...

    Makoto Miyazaki, Mariko Hayata, Noriaki Samukawa, Kazunori Iwanaga… in Scientific Reports (2020)

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