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  1. Article

    Open Access

    BCL3 expression is strongly associated with the occurrence of breast cancer relapse under tamoxifen treatment in a retrospective cohort study

    Patients with estrogen receptor positive breast cancer are usually receiving an anti-estrogen therapy by either aromatase inhibitors or selective estrogen receptor mediators such as tamoxifen. Nevertheless, ac...

    Piotr Czapiewski, Maximilian Cornelius, Roland Hartig, Thomas Kalinski… in Virchows Archiv (2022)

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    Article

    G-protein-coupled estrogen receptor GPER-1 expression in hormone receptor-positive breast cancer is associated with poor benefit of tamoxifen

    The role of G-protein-coupled estrogen receptor 1 (GPER-1) in the development of tamoxifen resistance in breast cancer is a highly controversial issue. The aim of this study was to determine the expression of ...

    Tanja Ignatov, Maria Claus, Norbert Nass… in Breast Cancer Research and Treatment (2019)

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    Article

    High neuronatin (NNAT) expression is associated with poor outcome in breast cancer

    Neuronatin (NNAT) is a proteolipid involved in cation homeostasis especially in the develo** brain. Its expression has been associated with the progression of lung cancer, glioblastoma, and neuroblastoma as ...

    Norbert Nass, Sarah Walter, Dörthe Jechorek, Christine Weissenborn… in Virchows Archiv (2017)

  4. No Access

    Article

    Accumulation of the advanced glycation end product carboxymethyl lysine in breast cancer is positively associated with estrogen receptor expression and unfavorable prognosis in estrogen receptor-negative cases

    Advanced glycation end products (AGEs) accumulate as a result of high concentrations of reactive aldehydes, oxidative stress, and insufficient degradation of glycated proteins. AGEs are therefore accepted biom...

    Norbert Nass, Atanas Ignatov, Ludwig Andreas… in Histochemistry and Cell Biology (2017)

  5. No Access

    Article

    Systemic activation of NF-κB driven luciferase activity in transgenic mice fed advanced glycation end products modified albumin

    Advanced glycation end products (AGEs) are stable end products of the Maillard reaction and accumulate with progressing ageing and degenerative diseases. Significant amounts of AGE-modified peptides are also c...

    Norbert Nass, Kristina Bayreuther, Andreas Simm in Glycoconjugate Journal (2017)

  6. No Access

    Article

    1,25-dihydroxyvitamin D3 inhibits corneal wound healing in an ex-vivo mouse model

    Impaired healing of corneal injuries can result in ulceration and complete loss of vision, especially in the elderly. Such patients frequently also exhibit vitamin D insufficiency. 1,25-dihydroxyvitamin D3 is the...

    Saadettin Sel, Stefanie Trau… in Graefe's Archive for Clinical and Experime… (2016)

  7. No Access

    Article

    Enzymes of urea synthesis are expressed at the ocular surface, and decreased urea in the tear fluid is associated with dry-eye syndrome

    The present study aims at determining whether enzymes of urea synthesis are expressed in the human lacrimal gland and in tissues of ocular surface (conjunctiva, cornea), to give evidence for the hypothesis tha...

    Kristin Jäger, Heike Kielstein… in Graefe's Archive for Clinical and Experime… (2013)

  8. No Access

    Article

    Enhanced luciferin entry causes rapid wound-induced light emission in plants expressing high levels of luciferase

    In-vivo imaging of transgenic tobacco plants (Nicotiana tobacum L.) expressing firefly luciferase under the control of the Arabidopsis phenylalanine ammonia-lyase 1 (PAL1)-promoter showed that luciferase-catalyz...

    Norbert Nass, Dierk Scheel in Planta (2001)

  9. No Access

    Article

    A retrotransposon-like sequence linked to the S-locus ofNicotiana alata is expressed in styles in response to touch

    We have identified a family of repetitive sequences in the genome ofNicotiana alata namedTnal (Transposon ofN. alata). The first element we characterised was on a genomic clone for theN. alata S6-ribonuclease (S6

    Joaquin Royo, Norbert Nass, Daniel P. Matton… in Molecular and General Genetics MGG (1996)