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  1. Article

    Open Access

    HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells

    HACE1, an E3 ubiquitin-protein ligase, is frequently inactivated and has been evidenced as a putative tumor suppressor in different types of cancer. However, its role in glioma remains elusive. Here, we observ...

    Chenxing Da, Jun Pu, Zhe Liu, **g Wei… in Signal Transduction and Targeted Therapy (2021)

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  2. Article

    Open Access

    CYP2S1 is a synthetic lethal target in BRAFV600E-driven thyroid cancers

    BRAFV600E is the most common genetic alteration and has become a major therapeutic target in thyroid cancers; however, intrinsic feedback mechanism limited clinical use of BRAFV600E specific inhibitors. Synthetic...

    Yiqi Li, ** Su, Chao Feng, Siyu Liu… in Signal Transduction and Targeted Therapy (2020)

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  3. No Access

    Article

    Comparison and Effects of Acute Lamotrigine Treatment on Extracellular Excitatory Amino Acids in the Hippocampus of PTZ-Kindled Epileptic and PTZ-Induced Status Epilepticus Rats

    In this communication, the effect of acute treatment with lamotrigine (LTG) was investigated on release of main excitatory amino acids (EAA) such as glutamate (Glu) and aspartate (Asp) in the hippocampus of pe...

    Yan Deng, Minghuan Wang, Wei Wang, Chao Ma, Nongyue He in Neurochemical Research (2013)

  4. No Access

    Protocol

    High-Throughput SNP Detection Based on PCR Amplification on Magnetic Nanoparticles Using Dual-Color Hybridization

    A microarray-based method for detecting single nucleotide polymorphisms (SNPs) using solid-phase polymerase chain reaction (PCR) on magnetic nanoparticles (MNPs) was developed. In this method one primer with a...

    Nongyue He, Song Li, Hongna Liu in Single Nucleotide Polymorphisms (2009)