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Article
Contrast‑associated acute kidney injury in myocardial infarction patients undergoing elective percutaneous coronary intervention: insight from the Iodixanol-AKI Registry
Previous studies have reported a high occurrence of contrast-associated acute kidney injury (CA-AKI) in myocardial infarction (MI) patients undergoing primary percutaneous coronary intervention (PCI). However,...
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Article
S-scheme heterojunction phthalocyanine/TiO2 photoelectrochemical sensor for innovative glutathione detection
A novel photoelectrochemical sensor, employing an S-scheme heterojunction of phthalocyanine and TiO2 nanoparticles, has been developed to enable highly sensitive determination of glutathione. By integrating the f...
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Article
The landscape of programmed cell death-related lncRNAs in Alzheimer’s disease and Parkinson’s disease
This study delivers a thorough analysis of long non-coding RNAs (lncRNAs) in regulating programmed cell death (PCD), vital for neurodegenerative diseases like Alzheimer’s disease (AD) and Parkinson’s disease (...
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Article
A new method of rolling finishing forming process of spiral bevel gears investigated by numerical simulation and experiment
Hot rolling forming enhances the overall mechanical performance of spiral bevel gears. However, it introduces challenges including high-forming temperatures (above 850°C), extensive deformation and oxidation o...
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Article
Open AccessTranscriptome analysis of Kunming mice responses to the bite of Xenopsylla cheopis
Flea bites could trigger a series of complex molecular responses in the host. However, our understanding of the responses at the molecular level is still relatively limited. This study quantifies the changes i...
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Article
State Observer-Based Composite Adaptive Fault-Tolerant Fuzzy Control for Uncertain Nonlinear Systems with Quantized Inputs
This work researches the issue of adaptive fault-tolerant fuzzy tracking control for a class of nonlinear systems in strict-feedback form with quantized inputs. The fuzzy logic systems are utilized to approxim...
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Article
A review on vanadium extraction techniques from major vanadium-containing resources
The critical role of vanadium in metallurgy and the increasing commercialization of vanadium redox flow batteries have contributed to a rise in market demand for vanadium, emphasizing the need to ensure the su...
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Article
Open AccessDeep-learning segmentation to select liver parenchyma for categorizing hepatic steatosis on multinational chest CT
Unenhanced CT scans exhibit high specificity in detecting moderate-to-severe hepatic steatosis. Even though many CTs are scanned from health screening and various diagnostic contexts, their potential for hepat...
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Article
Open AccessUnraveling resistance mechanisms in anti-CD19 chimeric antigen receptor-T therapy for B-ALL: a novel in vitro model and insights into target antigen dynamics
Cellular immunotherapy, represented by the chimeric antigen receptor T cell (CAR-T), has exhibited high response rates, durable remission, and safety in vitro and in clinical trials. Unfortunately, anti-CD19 C...
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Article
4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia
Abnormal activation of microglia, the resident macrophages in the central nervous system, plays an important role in the pathogenesis of multiple sclerosis (MS). The immune responsive gene 1(IRG1)/itaconate ax...
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Article
Open AccessA “twelve-section ultrasonic screening and diagnosis method” and management system for screening and treating neonatal congenital heart disease at the grassroots level in Tang County, Hebei Province, China
To explore a method for screening and diagnosing neonatal congenital heart disease (CHD) applicable to grassroots level, evaluate the prevalence of CHD, and establish a hierarchical management system for CHD s...
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Article
Open AccessAccuracy of dynamic navigation compared to static surgical guides and the freehand approach in implant placement: a prospective clinical study
Computer-guided implant surgery has improved the quality of implant treatment by facilitating the placement of implants in a more accurate manner. This study aimed to assess the accuracy of implant placement i...
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Article
Open AccessAcacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Myocarditis refers to an autoimmune inflammatory response of the myocardium with characterization of self-reactive CD4+ T cell activation, which lacks effective treatment and has a poor prognosis. Acacetin is ...
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Article
Open AccessEvaluating the clinical efficacy and safety of concurrent chemoradiotherapy with cisplatin and nab-paclitaxel in postoperative early-stage cervical cancer
A preclinical study showed that nab-paclitaxel acted as a radiosensitizer and improved tumor radiotherapy in a supra-additive manner. In this study, we aimed to evaluate the clinical efficacy and safety of con...
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Article
Open AccessAnthropogenic eutrophication and stratification strength control hypoxia in the Yangtze Estuary
Many large estuaries are threatened by intensifying hypoxia. However, due to the limited duration of available observations, uncertainties persist regarding the level of contemporary hypoxia intensity in a lon...
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Article
Open AccessMultimodal analysis of cfDNA methylomes for early detecting esophageal squamous cell carcinoma and precancerous lesions
Detecting early-stage esophageal squamous cell carcinoma (ESCC) and precancerous lesions is critical for improving survival. Here, we conduct whole-genome bisulfite sequencing (WGBS) on 460 cfDNA samples from ...
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Article
Fabrication of Polypyrrole/Reduced Graphene Oxide/Silk as a High-Performance Electrode for Fiber-Shaped Flexible Supercapacitor
Fiber-shaped supercapacitors (FSSCs), as a very new variety of flexible power source, are strongly needed for smart electronics, but the preparation still remains challenging. In this study, using silk fiber (...
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Article
Open AccessThoracolumbar fractures patients undergoing posterior pedicle screw fixation can benefit from drainage
To explore whether it is necessary to put drain tubes after posterior pedicle screw fixation of thoracolumbar fractures.
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Article
An approximate grinding and deviation correction method for helical face gear
This paper introduces an approximate grinding method (AGM) and tooth flank deviation correction strategies for helical face gears (HFGs) generated by grinding worm, addressing the issue of singularities on the...
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Article
Open AccessLarge spread in marine heatwave assessments for Asia and the Indo-Pacific between sea-surface-temperature products
Prolonged extremely warm ocean temperatures have great impacts on both natural ecosystems and human communities. These phenomena (i.e., marine heatwaves) could be easily monitored globally by satellite-based s...
