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Article
Open AccessPhysical activity and its impact on cardiovascular health in pediatric kidney transplant recipients
Cardiovascular (CV) morbidity after kidney transplantation (KTx) in childhood is of increasing importance. In light of a high prevalence of CV risk factors, protective measures such as physical activity (PA) c...
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Article
Open AccessLMS-based continuous pediatric reference values for soluble receptor activator of nuclear factor kappa B ligand (sRANKL) and osteoprotegerin (OPG) in the HARP cohort
Soluble RANKL (sRANKL) and osteoprotegerin (OPG) are regulators of osteoclast differentiation and activation, but adequate pediatric reference values are lacking. Here we provide LMS (Lambda-Mu-Sigma)-based co...
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Article
Open AccessThe significance of central blood pressure for cardiovascular target organ damage in children and adolescents after kidney transplantation
Cardiovascular (CV) complications are important causes of morbidity and mortality in children after kidney transplantation (KTx). In adults, central blood pressure (cBP) is an accepted predictor of CV sequelae...
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Article
Open AccessArterial stiffness and blood pressure increase in pediatric kidney transplant recipients
Pulse wave velocity (PWV) is a measure of arterial stiffness. We investigated PWV and blood pressure (BP) to determine to what extent BP changes contribute to arterial stiffness, and secondly, to identify infl...
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Article
Open AccessImpact of Sex and Obesity on Echocardiographic Parameters in Children and Adolescents
Subclinical alterations in left ventricular structure and function are detectable in adolescents with hypertension or obesity. However, data on early echocardiographic abnormalities in seemingly healthy childr...
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Article
Sex and age as determinants for high blood pressure in pediatric renal transplant recipients: a longitudinal analysis of the CERTAIN Registry
High prevalence of arterial hypertension is known in pediatric renal transplant patients, but how blood pressure (BP) distribution and control differ between age groups and whether sex and age interact and pot...
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Article
Open AccessPublisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessHuman DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis
Immune responses need to be controlled tightly to prevent autoimmune diseases, yet underlying molecular mechanisms remain partially understood. Here, we identify biallelic mutations in three patients from two ...
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Article
Cardiovascular risk factors and subclinical organ damage after hematopoietic stem cell transplantation in pediatric age
Advances in allogeneic hematopoietic stem cell transplantation (HSCT) in malignant and non-malignant diseases result in more long-term survivors, in whom cardiovascular (CV) disease is one leading non-cancer c...
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Article
Correction to: Relationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain
The original version of this article unfortunately contained an error in a couple of reference citation in Discussion Section, paragraph 6. The reference citation number should be changed from [6] to [9] in th...
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Article
Open AccessRelationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain
Limited valid data are available regarding the association of fructose-induced symptoms, fructose malabsorption, and clinical symptoms.
