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  1. No Access

    Article

    Developmental neurotoxicity of cadmium on enzyme activities of crucial offspring rat brain regions

    Cadmium (Cd) is an environmental contaminant known to exert significant neurotoxic effects on both humans and experimental animals. The aim of this study was to shed more light on the effects of gestational (i...

    Vasileios Stolakis, Stylianos Tsakiris, Konstantinos Kalafatakis… in BioMetals (2013)

  2. No Access

    Article

    Modulation of crucial adenosinetriphosphatase activities due to U-74389G administration in a porcine model of intracerebral hemorrhage

    Spontaneous intracerebral hemorrhage (ICH) represents a partially-understood cerebrovascular disease of high incidence, morbidity and mortality. We, herein, report the findings of our study concerning the role...

    Alexios Bimpis, Apostolos Papalois, Stylianos Tsakiris… in Metabolic Brain Disease (2013)

  3. No Access

    Article

    Experimentally-induced Wernicke’s encephalopathy modifies crucial rat brain parameters: the importance of Na+,K+-ATPase and a potentially neuroprotective role for antioxidant supplementation

    Wernicke’s encephalopathy (WE) is a serious neuropsychiatric syndrome caused by chronic alcoholism and thiamine (T) deficiency. Our aim was to shed more light on the pathophysiology of WE, by introducing a mod...

    Apostolos Zarros, Charis Liapi, Hussam Al-Humadi… in Metabolic Brain Disease (2013)

  4. No Access

    Article

    Short-Term Exposure to Nickel Alters the Adult Rat Brain Antioxidant Status and the Activities of Crucial Membrane-Bound Enzymes: Neuroprotection by L-Cysteine

    Nickel (Ni) is an environmental pollutant towards which human exposure can be both occupational (mainly through inhalation) and dietary (through water and food chain-induced bioaccumulation). The aim of this s...

    Charis Liapi, Apostolos Zarros, Stamatios Theocharis… in Biological Trace Element Research (2011)

  5. No Access

    Article

    Combined thirty-day exposure to thioacetamide and choline-deprivation alters serum antioxidant status and crucial brain enzyme activities in adult rats

    Choline (Ch) is an essential nutrient that seems to be involved in a wide variety of metabolic reactions and functions that affect the nervous system, while thioacetamide (TAA) is a well-known hepatotoxic agen...

    Charis Liapi, Hussam Al-Humadi, Apostolos Zarros… in Metabolic Brain Disease (2009)

  6. No Access

    Article

    Effects of adult-onset streptozotocin-induced diabetes on the rat brain antioxidant status and the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase: modulation by L-cysteine

    Uncontrolled diabetes is known to affect the nervous system. The aim of this study was to investigate the effect of the antioxidant L-cysteine (Cys) on the changes caused by adult-onset streptozotocin (STZ)-induc...

    Apostolos Zarros, Charis Liapi, Panagiota Galanopoulou… in Metabolic Brain Disease (2009)

  7. No Access

    Article

    The neuroprotective role of l-cysteine towards the effects of short-term exposure to lanthanum on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase

    Lanthanum (La) is a rare earth element that is widely used for industrial, medical and agricultural purposes. Its neurotoxic effects are linked to its physical and chemical properties and its interaction with ...

    Charis Liapi, Apostolos Zarros, Stamatios Theocharis, Hussam Al-Humadi… in BioMetals (2009)

  8. No Access

    Article

    Effects of fulminant hepatic encephalopathy on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase: comparison of the enzymes’ response to in vitro treatment with ammonia

    Hepatic encephalopathy can be a life-threatening complication of fulminant hepatic failure. By understanding the pathophysiology involved in the induction of this neuropsychiatric disorder, future therapeutic ...

    Apostolos Zarros, Stamatios Theocharis, Nikolina Skandali… in Metabolic Brain Disease (2008)