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  1. No Access

    Chapter and Conference Paper

    Efficient Evaluation of Conjunctive Regular Path Queries Using Multi-way Joins

    Recent analyses of real-world queries show that a prominent type of queries is that of conjunctive regular path queries. Despite the increasing popularity of this type of queries, only limited efforts have bee...

    Nikolaos Karalis, Alexander Bigerl, Liss Heidrich, Mohamed Ahmed Sherif in The Semantic Web (2024)

  2. Article

    Open Access

    Breathing coordinates cortico-hippocampal dynamics in mice during offline states

    Network dynamics have been proposed as a mechanistic substrate for the information transfer across cortical and hippocampal circuits. However, little is known about the mechanisms that synchronize and coordina...

    Nikolaos Karalis, Anton Sirota in Nature Communications (2022)

  3. No Access

    Article

    Intercalated amygdala clusters orchestrate a switch in fear state

    Adaptive behaviour necessitates the formation of memories for fearful events, but also that these memories can be extinguished. Effective extinction prevents excessive and persistent reactions to perceived thr...

    Kenta M. Hagihara, Olena Bukalo, Martin Zeller, Ayla Aksoy-Aksel in Nature (2021)

  4. No Access

    Chapter and Conference Paper

    Extending the YAGO2 Knowledge Graph with Precise Geospatial Knowledge

    We extend YAGO2 with geospatial information represented by geometries (e.g., lines, polygons, multipolygons, etc.) encoded by Open Geospatial Consortium standards. The new geospatial information comes from off...

    Nikolaos Karalis, Georgios Mandilaras, Manolis Koubarakis in The Semantic Web – ISWC 2019 (2019)

  5. Article

    Open Access

    IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses

    Abnormalities in synaptic inhibition play a critical role in psychiatric disorders, and accordingly, it is essential to understand the molecular mechanisms linking components of the inhibitory postsynapse to p...

    Olga Babaev, Hugo Cruces-Solis, Carolina Piletti Chatain in Nature Communications (2018)

  6. No Access

    Article

    Prefrontal neuronal assemblies temporally control fear behaviour

    In the dorsal medial prefrontal cortex, expression of conditioned fear is causally related to the organization of neurons into functional assemblies, defining tight temporal control of this behaviour.

    Cyril Dejean, Julien Courtin, Nikolaos Karalis, Fabrice Chaudun, Hélène Wurtz in Nature (2016)

  7. No Access

    Article

    4-Hz oscillations synchronize prefrontal–amygdala circuits during fear behavior

    This study demonstrates that fear memory expression is driven by 4-Hz oscillations in prefrontal–amygdala circuits. During fear behavior, prefrontal 4-Hz oscillations lead amygdala and synchronize spiking acti...

    Nikolaos Karalis, Cyril Dejean, Fabrice Chaudun, Suzana Khoder in Nature Neuroscience (2016)

  8. No Access

    Article

    Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression

    Single-unit recordings and optogenetic manipulations in mice undergoing auditory fear conditioning show that fear expression is related to the phasic inhibition of prefrontal cortex (PFC) parvalbumin interneur...

    Julien Courtin, Fabrice Chaudun, Robert R. Rozeske, Nikolaos Karalis in Nature (2014)