Skip to main content

and
  1. Article

    Open Access

    Vaccination status and self-reported side effects after SARS-CoV-2 vaccination in relation to psychological and clinical variables in patients with multiple sclerosis

    The recent SARS-CoV-2 pandemic and the vaccination campaign posed a challenge to patients with autoimmune disease, such as multiple sclerosis (MS). We aimed for investigating whether psychological/sociodemogra...

    Katja Burian, Felicita Heidler, Niklas Frahm, Michael Hecker in Scientific Reports (2024)

  2. Article

    Open Access

    Application of Statistical Methods for Central Statistical Monitoring and Implementations on the German Multiple Sclerosis Registry

    Monitoring of clinical trials is a fundamental process required by regulatory agencies. It assures the compliance of a center to the required regulations and the trial protocol. Traditionally, monitoring teams...

    Firas Fneish, David Ellenberger in Therapeutic Innovation & Regulatory Science (2023)

  3. Article

    Open Access

    Vaccination willingness in association with personality traits in patients with multiple sclerosis in the course of SARS-CoV-2 pandemic

    Vaccination is a key strategy for controlling the SARS-CoV-2 pandemic. Acceptance of SARS-CoV-2 vaccines by chronically ill patients, such as multiple sclerosis (MS) patients, plays an important role in preven...

    Felicita Heidler, Julia Baldt, Niklas Frahm, Silvan Elias Langhorst in Scientific Reports (2022)

  4. Article

    Open Access

    Therapy Switches in Fingolimod-Treated Patients with Multiple Sclerosis: Long-Term Experience from the German MS Registry

    Therapy switches in patients with multiple sclerosis (MS) receiving treatment with fingolimod occur frequently in clinical practice but are not well represented in real-world data. The aim of this study was to...

    Niklas Frahm, Firas Fneish, David Ellenberger, Peter Flachenecker in Neurology and Therapy (2022)

  5. Article

    Open Access

    Polypharmacy in patients with multiple sclerosis: a gender-specific analysis

    Multiple sclerosis (MS) affects about three times more women than men. Due to variable MS courses, multiple therapies are necessary in clinical practice.

    Niklas Frahm, Michael Hecker, Uwe Klaus Zettl in Biology of Sex Differences (2019)

  6. Article

    Open Access

    Multi-drug use among patients with multiple sclerosis: A cross-sectional study of associations to clinicodemographic factors

    Multiple sclerosis (MS) is the most prevalent immune-mediated disease affecting the central nervous system. A treatment strategy with multiple therapies is a frequent clinical scenario. Unmonitored multi-drug ...

    Niklas Frahm, Michael Hecker, Uwe Klaus Zettl in Scientific Reports (2019)