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Article
Open AccessOntology based molecular signatures for immune cell types via gene expression analysis
New technologies are focusing on characterizing cell types to better understand their heterogeneity. With large volumes of cellular data being generated, innovative methods are needed to structure the resultin...
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Article
Open AccessThe Cell Ontology 2016: enhanced content, modularization, and ontology interoperability
The Cell Ontology (CL) is an OBO Foundry candidate ontology covering the domain of canonical, natural biological cell types. Since its inception in 2005, the CL has undergone multiple rounds of revision and ex...
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Article
Open AccessOntologizing health systems data at scale: making translational discovery a reality
Common data models solve many challenges of standardizing electronic health record (EHR) data but are unable to semantically integrate all of the resources needed for deep phenoty**. Open Biological and Biom...
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Article
Open AccessAn open source knowledge graph ecosystem for the life sciences
Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face s...