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Article
Open AccessGalacto-oligosaccharide preconditioning improves metabolic activity and engraftment of Limosilactobacillus reuteri and stimulates osteoblastogenesis ex vivo
A probiotic-related benefit for the host is inherently linked to metabolic activity and integration in the gut ecosystem. To facilitate these, probiotics are often combined with specific prebiotics in a synbio...
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Article
Open AccessHigh flow nasal oxygen therapy to avoid invasive mechanical ventilation in SARS-CoV-2 pneumonia: a retrospective study
The efficacy of high flow nasal canula oxygen therapy (HFNO) to prevent invasive mechanical ventilation (IMV) is not well established in severe coronavirus disease 2019 (COVID-19). The aim of this study was to...
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Article
Computer-aided design (CAD) compensation through modeling of shrinkage in additively manufactured parts
Despite the advantages that additive manufacturing (AM) processes present and the progressive number of activity sectors that they emerge in, their successful adoption is currently hampered by defects in surfa...
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Article
The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis
Periostin is an extracellular matrix protein that actively contributes to tumor progression and metastasis. Here, we hypothesized that it could be a marker of bone metastasis formation. To address this questio...
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Article
Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone
Periostin is a matricellular protein mainly expressed by periosteal cells and osteocytes in bone, but is also present in several other tissues. Available immunoassays use antibodies of unclear specificity. The...
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Article
Bone-Derived Factors: A New Gateway to Regulate Glycemia
Type 2 diabetes mellitus (T2DM) and osteoporosis are two major disorders which prevalence increases with aging and is predicted to worsen in the coming years. Preclinical investigations suggest common mechanis...
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Article
Influence of Fatigue Loading and Bone Turnover on Bone Strength and Pattern of Experimental Fractures of the Tibia in Mice
Bone fragility depends on bone mass, structure, and material properties, including damage. The relationship between bone turnover, fatigue damage, and the pattern and location of fractures, however, remains po...
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Chapter
Silvio’s Party
Italy is going through a new crisis in its party system comparable in many respects to the one that brought down the First Republic at the beginning of the 1990s. On 12 November 2011, against the background of...
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Article
Development of a New ELISA for Serum Periostin: Evaluation of Growth-Related Changes and Bisphosphonate Treatment in Mice
Periostin is a gamma-carboxyglutamic acid protein preferentially expressed in periosteum and bone mesenchymal stem cells. Lack of a precise assay for measuring circulating levels impairs the investigation of i...
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Article
Open AccessInfluence of hypoxia on the domiciliation of Mesenchymal Stem Cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies?
Bone marrow (BM) cells are promising tools for vascular therapies. Here, we focused on the possibility of targeting the hypoxia-induced pulmonary artery hypertension remodeling with systemic delivery of BM-der...
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Chapter and Conference Paper
MARGE Project: Design, Modeling and Control of Assistive Devices for Minimally Invasive Surgery
MARGE is a joint project in the framework of the interdisciplinary national program in Robotics, called ROBEA, launched by the French National Research Center (CNRS) in 2001. The focus is on the development of...
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Article
Left Ventricular Alterations in a Model of Fetal Left Ventricular Overload
Congenital aortic coarctation is well tolerated by the fetus because the foramen ovale and ductus arteriosus equalize intracardiac and great arteries pressures and shunts. The pathologic consequences only emer...
