5 Result(s)
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Article
Challenges and best practices in omics benchmarking
Technological advances enabling massively parallel measurement of biological features — such as microarrays, high-throughput sequencing and mass spectrometry — have ushered in the omics era, now in its third d...
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Article
Open AccessCAMPAREE: a robust and configurable RNA expression simulator
The accurate interpretation of RNA-Seq data presents a moving target as scientists continue to introduce new experimental techniques and analysis algorithms. Simulated datasets are an invaluable tool to accura...
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Open AccessA comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression
Though Illumina has largely dominated the RNA-Seq field, the simultaneous availability of Ion Torrent has left scientists wondering which platform is most effective for differential gene expression (DGE) analy...
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Article
Open AccessThe Nephila clavipes genome highlights the diversity of spider silk genes and their complex expression
Benjamin Voight and colleagues report the annotated genome of the golden orb-weaver spider. They describe 28 spider silk genes (spidroins), characterize their expression in distinct silk gland types and identi...
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Article
Open AccessIVT-seq reveals extreme bias in RNA sequencing
RNA-seq is a powerful technique for identifying and quantifying transcription and splicing events, both known and novel. However, given its recent development and the proliferation of library construction meth...
