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Article
Challenges and best practices in omics benchmarking
Technological advances enabling massively parallel measurement of biological features — such as microarrays, high-throughput sequencing and mass spectrometry — have ushered in the omics era, now in its third d...
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Article
Open AccessCAMPAREE: a robust and configurable RNA expression simulator
The accurate interpretation of RNA-Seq data presents a moving target as scientists continue to introduce new experimental techniques and analysis algorithms. Simulated datasets are an invaluable tool to accura...
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Article
Open AccessComparative evaluation of full-length isoform quantification from RNA-Seq
Full-length isoform quantification from RNA-Seq is a key goal in transcriptomics analyses and has been an area of active development since the beginning. The fundamental difficulty stems from the fact that RNA...