5 Result(s)
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Article
Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry
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Article
Dense genoty** identifies and localizes multiple common and rare variant association signals in celiac disease
David van Heel, Cisca Wijmenga and colleagues used a custom, high-density genoty** chip to examine 183 immune-related loci for their role in celiac disease. They report 13 new regions associated with celiac ...
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Article
Correction: Corrigendum: Multiple common variants for celiac disease influencing immune gene expression
Nat. Genet.; doi:10.1038/ng.543; corrected online 12 March 2010 In the version of this article initially published online, the P value ranges in the second paragraph of the Results section under (iii) and (iv)...
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Article
Multiple common variants for celiac disease influencing immune gene expression
David van Heel and colleagues report results of a large genome-wide association study of celiac disease. Most of the associated loci contain genes with immune functions, and over half harbor risk variants that...
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Article
A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia
We report the first identified mutation in the gene encoding human cytochrome c (CYCS). Glycine 41, invariant throughout eukaryotes, is substituted by serine in a family with autosomal dominant thrombocytopenia c...
