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  1. Article

    Open Access

    Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions

    Genetic factors play a major role in frontotemporal dementia (FTD). The majority of FTD cannot be genetically explained yet and it is likely that there are still FTD risk loci to be discovered. Common variants...

    Lianne M. Reus, Iris E. Jansen, Merel O. Mol, Fred van Ruissen in Translational Psychiatry (2021)

  2. Article

    Open Access

    Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes

    A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22613-2

    Joris Deelen, Daniel S. Evans, Dan E. Arking, Niccolò Tesi in Nature Communications (2021)

  3. Article

    Open Access

    Immune response and endocytosis pathways are associated with the resilience against Alzheimer’s disease

    Develo** Alzheimer’s disease (AD) is influenced by multiple genetic variants that are involved in five major AD-pathways. Per individual, these pathways may differentially contribute to the modification of t...

    Niccolò Tesi, Sven J. van der Lee, Marc Hulsman, Iris E. Jansen in Translational Psychiatry (2020)

  4. Article

    Open Access

    A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Human longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two meta-analyses of GWA studies of a rigorous longevity phenotype definition including 11,262...

    Joris Deelen, Daniel S. Evans, Dan E. Arking, Niccolò Tesi in Nature Communications (2019)