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Article
Open AccessPrecision prognostics for cardiovascular disease in Type 2 diabetes: a systematic review and meta-analysis
Precision medicine has the potential to improve cardiovascular disease (CVD) risk prediction in individuals with Type 2 diabetes (T2D).
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Article
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes ...
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Article
Machine Learning Models for Inpatient Glucose Prediction
Glucose management in the hospital is difficult due to non-static factors such as antihyperglycemic and steroid doses, renal function, infection, surgical status, and diet. Given these complex and dynamic fact...
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Inpatient Glycemic Management of Non-cardiac CVD: Focus on Stroke and PVD
Hyperglycemia occurs frequently in hospitalized patients with stroke and peripheral vascular disease (PVD). Guidelines for inpatient glycemic management are not well established for this patient population. We...
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The Case for Diabetes Population Health Improvement: Evidence-Based Programming for Population Outcomes in Diabetes
The goal of this review is to describe diabetes within a population health improvement framework and to review the evidence for a diabetes population health continuum of intervention approaches, including diab...
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A Comparison of Inpatient Glucose Management Guidelines: Implications for Patient Safety and Quality
Inpatient glucose management guidelines and consensus statements play an important role in hel** to keep hospitalized patients with diabetes and hyperglycemia safe and in optimizing the quality of their glyc...
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Expression of the pituitary stem/progenitor marker GFRα2 in human pituitary adenomas and normal pituitary
Recent studies suggest that adult pituitary stem cells may play a role in pituitary tumorigenesis. We sought to explore whether the Glial cell-line derived neurotrophic factor receptor alpha 2 (GFRα2), a recen...
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ACTH-secreting pituitary adenomas: size does not correlate with hormonal activity
ACTH-secreting pituitary adenomas (Cushing’s disease, CD) are the most frequent cause of Cushing’s syndrome. To test whether the size of ACTH-secreting adenomas correlates with the degree of biochemical and cl...
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Article
“Glandular intoxication” following emergent tracheotomy during transsphenoidal surgery for acromegaly: Cushing’s 1910 unrecognized case of thyroid storm?
Harvey Cushing’s monograph The Pituitary Body and Its Disorders describes Case XXXVIII, H. M. B., a 33 year-old man who presented with acromegaly in 1910. The detailed operative note reports an emergency tracheot...
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Pituitary tumors
Pituitary adenomas are the most common intrasellar tumors. With the exception of prolactinomas, first-line treatment is almost always surgical. Prolactinomas are usually treated with dopamine agonists such as ...