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Article
Open AccessInhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy
The multifaceted chemo-immune resistance is the principal barrier to achieving cure in cancer patients. Identifying a target that is critically involved in chemo-immune-resistance represents an attractive stra...
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Protocol
Expression and Purification of tRNA/ pre-miRNA-Based Recombinant Noncoding RNAs
Research on RNA function and therapeutic potential is dominated by the use of chemoengineered RNA mimics. Recent efforts have led to the establishment of novel technologies for the production of recombinant or...
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Article
Novel approaches for efficient in vivo fermentation production of noncoding RNAs
Genome-derived noncoding RNAs (ncRNAs), including microRNAs (miRNAs), small interfering RNAs (siRNAs), and long noncoding RNAs (lncRNAs), play an essential role in the control of target gene expression underly...
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Article
Bioengineering of a single long noncoding RNA molecule that carries multiple small RNAs
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), small interfering RNAs (siRNAs), and long noncoding RNAs (lncRNAs), regulate target gene expression and can be used as tools for understanding biological ...
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Article
Open AccessMechanism of gallic acid biosynthesis in bacteria (Escherichia coli) and walnut (Juglans regia)
Gallic acid (GA), a key intermediate in the synthesis of plant hydrolysable tannins, is also a primary anti-inflammatory, cardio-protective agent found in wine, tea, and cocoa. In this publication, we reveal t...
