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Article
Molecular assays for determining sulphadoxine-pyrimethamine drug resistance in India: a systematic review
A plethora of studies analyse the molecular markers of drug resistance and hence help in guiding the evidence-based malaria treatment policies in India. For reporting mutations, a number of techniques includin...
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Article
Diagnostic performance of rapid diagnostic test, light microscopy and polymerase chain reaction during mass survey conducted in low and high malaria-endemic areas from two North-Eastern states of India
An early and accurate diagnosis followed by prompt treatment is pre-requisite for the management of any disease. Malaria diagnosis is routinely performed by microscopy and rapid diagnostic tests (RDTs) in the ...
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Article
Redox interactome in malaria parasite Plasmodium falciparum
The malaria-causing parasite Plasmodium falciparum is a severe threat to human health across the globe. This parasite alone causes the highest morbidity and mortality than any other species of Plasmodium. The par...
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Chapter and Conference Paper
Robotic Waiters: Detecting Table to Serve Using RFID Tags
Robots are now providing services in the field of hospitality in China and Japan. They are using a guided path to navigate and serve the food to the table, from where the order comes. Detecting and stop toward...
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Chapter and Conference Paper
Design Process and Stress Analysis of Spine in Humanoid Serving Robot to Provide Proper Balancing and Load Bearing Capabilities
Designing a robot that looks like human always gives the better experience in human–robot interaction. It is an important part along with the technology use in it because majorly public got attract toward robo...
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Article
Open AccessEfficacy of two artemisinin-based combinations for the treatment of malaria in pregnancy in India: a randomized controlled trial
In India, the recommended first-line treatment for malaria in the second and third trimester of pregnancy is artesunate + sulfadoxine-pyrimethamine (AS+SP). However, data on safety and efficacy of artemisinin-...
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Article
Open AccessQuantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group
The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Viv...
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Article
Open AccessEstablishment and application of a novel isothermal amplification assay for rapid detection of chloroquine resistance (K76T) in Plasmodium falciparum
Chloroquine (CQ) resistance in Plasmodium falciparum is determined by the mutations in the chloroquine resistance transporter (Pfcrt) gene. The point mutation at codon 76 (K76T), which has been observed in more t...
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Article
Open AccessEmerging polymorphisms in falciparum Kelch 13 gene in Northeastern region of India
Recent reports of emergence and spread of artemisinin resistance in the Southeast Asia region, including Myanmar, pose a greater threat to malaria control and elimination in India. Whole genome sequencing stud...
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Article
Open AccessComputer-vision-based technology for fast, accurate and cost effective diagnosis of malaria
Microscopy has long been considered to be the gold standard for diagnosis of malaria despite the introduction of newer assays. However, it has many challenges like requirement of trained microscopists and log...
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Article
Monitoring artemisinin resistance in Plasmodium falciparum: comparison of parasite clearance time by microscopy and real-time PCR and evaluation of mutations in Pfatpase6 gene in Odisha state of India
Antimalarial drug resistance including artemisinin resistance in Plasmodium falciparum malaria is a major concern in combating malaria throughout the world. Delayed parasite clearance time (PCT) is indicative of ...
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Article
Open AccessDeclining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India
Anti-malarial drug resistance in Plasmodium falciparum in India has historically travelled from northeast India along the Myanmar border. The treatment policy for P. falciparum in the region was, therefore, chang...
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Article
Coordination chemistry of Schiff base tin complexes
The most important results of extensive studies of tin metal complexes with Schiff base ligands are reviewed. A large number of inorganic compounds are known but still there is a need of new compounds to devel...
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Article
Open AccessChloroquine efficacy studies confirm drug susceptibility of Plasmodium vivax in Chennai, India
Assessing the Plasmodium vivax burden in India is complicated by the potential threat of an emerging chloroquine (CQ) resistant parasite population from neighbouring countries in Southeast Asia. Chennai, the capi...
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Article
Open AccessA clinical and molecular study of artesunate + sulphadoxine-pyrimethamine in three districts of central and eastern India
Artesunate + sulphadoxine-pyrimethamine (AS + SP) is recommended throughout India as the first-line treatment for uncomplicated falciparum malaria. Due to the presence of several eco-epidemiological zones of m...
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Article
Open AccessGenetic variation in histidine rich proteins among Indian Plasmodium falciparum population: possible cause of variable sensitivity of malaria rapid diagnostic tests
Rapid diagnostic tests (RDTs) have revolutionized the diagnosis of malaria. Among the various factors affecting RDTs sensitivity is genetic variation of the antigen used. The genetic variation in PfHRP2 and Pf...
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Article
Open AccessPrescription practices and availability of artemisinin monotherapy in India: where do we stand?
The World Health Organization has urged all member states to deploy artemisinin-based combination therapy and progressively withdraw oral artemisinin monotherapies from the market due to their high recrudescen...
