2 Result(s)
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Nathalie Daude
Life Sciences
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Article
Open AccessPathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope
The microtubule-associated protein tau forms aggregates in different neurodegenerative diseases called tauopathies. Prior work has shown that a single P301L mutation in tau gene, MAPT, can promote alternative tau...
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Chapter
Familial Prion Diseases Modeled in Cell Culture
The central pathogenic event in prion diseases is the posttranslational conversion of PrPC, a normal cell-surface glycoprotein, into PrPSc, the principal constituent of infectious prion particles (reviewed by Pru...
