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Open AccessDevelopment of a chemogenomics library for phenotypic screening
With the development of advanced technologies in cell-based phenotypic screening, phenotypic drug discovery (PDD) strategies have re-emerged as promising approaches in the identification and development of nov...
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Open AccessImpacts of drug resistance mutations on the structural asymmetry of the HIV-2 protease
Drug resistance is a severe problem in HIV treatment. HIV protease is a common target for the design of new drugs for treating HIV infection. Previous studies have shown that the crystallographic structures of...
