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  1. Article

    Open Access

    Long-term follow-up of 109 children with juvenile idiopathic oligoarthritis after first intra-articular corticosteroid injection

    To evaluate long-term outcomes and prognostic factors in patients with juvenile idiopathic arthritis (JIA), presenting as oligoarthritis, who received IAC as the first treatment for their disease.

    Mojca Zajc Avramovič, Nataša Toplak, Gašper Markelj in Arthritis Research & Therapy (2024)

  2. Article

    Open Access

    Disease relapse rate in children with autoimmune rheumatic diseases after COVID-19 infection and vaccination

    Paediatric patients with autoimmune rheumatic diseases (pARD) are often immunocompromised because of the disease and/or the therapy they receive. At the beginning of COVID-19 pandemic there was a great concern...

    Tjaša Šinkovec Savšek, Mojca Zajc Avramovič, Tadej Avčin in Pediatric Rheumatology (2023)

  3. No Access

    Chapter and Conference Paper

    Anti-adhesion Activity of Phenolic Compounds Against Campylobacter jejuni and Listeria monocytogenes Evaluated with PCR-Based Methods

    Campylobacter jejuni and Listeria monocytogenes are food-borne zoonotic bacteria with the highest notification rate and the highest death rate in EU, respectively. Both bacteria form biofilms on surfaces with the...

    Sonja Smole Možina, Meta Sterniša, Gaja Pretnar in 10th Central European Congress on Food (2022)

  4. No Access

    Article

    Vaccination for Children on Biologics

    Several biologic drugs are available for treatment of immune-mediated diseases, and the number of children treated with biologics is increasing. This review summarises current knowledge about the safety and im...

    Nataša Toplak, Yosef Uziel in Current Rheumatology Reports (2020)

  5. Article

    Open Access

    Identification of novel reassortant mammalian orthoreoviruses from bats in Slovenia

    Recently, mammalian orthoreoviruses (MRVs) were detected for the first time in European bats, and the closely related strain SI-MRV01 was isolated from a child with severe diarrhoea in Slovenia. Genetically si...

    Tina Naglič, Danijela Rihtarič, Peter Hostnik, Nataša Toplak in BMC Veterinary Research (2018)

  6. Article

    Open Access

    Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two

    Olga Lomakina, Ekaterina Alekseeva, Sania Valieva in Pediatric Rheumatology (2017)

  7. Article

    Open Access

    Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part three

    Riccardo Papa, Alessandro Consolaro, Francesca Minoia in Pediatric Rheumatology (2017)

  8. Article

    Open Access

    Clinical and MRI outcome of cervical spine lesions in children with juvenile idiopathic arthritis treated with anti-TNFα drugs early in disease course

    The purpose of the study was to evaluate the clinical and magnetic resonance imaging (MRI) outcome of cervical spine arthritis in children with juvenile idiopathic arthritis (JIA), who received anti-TNFα early...

    Damjana Ključevšek, Nina Emeršič, Nataša Toplak, Tadej Avčin in Pediatric Rheumatology (2017)

  9. No Access

    Article

    Acute rheumatic fever outbreak in southern central European country

    A decline in the incidence of acute rheumatic fever (ARF) in developed countries over the past century can be attributed to the improved public hygiene and to widespread use of antibiotics. ARF seemed to be a ...

    Urška Kočevar, Nataša Toplak, Blaž Kosmač, Luka Kopač in European Journal of Pediatrics (2017)

  10. No Access

    Article

    Management of Juvenile Idiopathic Arthritis: A Clinical Guide

    Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood. The outcome in patients with JIA has markedly improved with the advent of biologic drugs. Although early aggressiv...

    Štefan Blazina, Gašper Markelj, Mojca Zajc Avramovič, Nataša Toplak in Pediatric Drugs (2016)

  11. No Access

    Article

    Autoimmune and Inflammatory Manifestations in 247 Patients with Primary Immunodeficiency—a Report from the Slovenian National Registry

    An abnormal regulation of immune responses leads to autoimmune and inflammatory manifestations in patients with primary immunodeficiencies (PIDs). The objective of our study was to evaluate the frequency of no...

    Štefan Blazina, Gašper Markelj, Anja Koren Jeverica in Journal of Clinical Immunology (2016)

  12. Article

    Open Access

    Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation

    The Mediterranean fever (MEFV) gene codes for protein pyrin, one of the regulators of inflammasome activity in innate immune cells. Mutations in this gene are considered the primary cause of Familial Mediterranea...

    Jelena Milenković, Jelena Vo**ović, Maruša Debeljak in Pediatric Rheumatology (2016)

  13. Article

    Open Access

    Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature

    Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease assoc...

    Katarina Sedej, Nataša Toplak, Marina Praprotnik, Boštjan Luzar in Pediatric Rheumatology (2015)

  14. Article

    Open Access

    Genetic determinants of methotrexate treatment efficacy in patients with juvenile idiopathic arthritis

    Mojca Zajc Avramovič, Nataša Toplak, Meta Accetto in Pediatric Rheumatology (2014)

  15. Article

    Open Access

    MEFV and NLRP3 gene variants in children with pfapa syndrome in slovenia

    Daša Perko, Maruša Debeljak, Nataša Toplak, Tadej Avčin in Pediatric Rheumatology (2014)

  16. Article

    Exploring the Binding Sites of Anti-Infliximab Antibodies in Pediatric Patients With Rheumatic Diseases Treated With Infliximab

    Over the past decade, the treatment of a variety of immune-mediated diseases has improved greatly due to the introduction of biologics for therapies in cases that are nonresponsive to traditional treatments. H...

    Miha Kosmač, Tadej Avčin, Nataša Toplak, Gabriele Simonini in Pediatric Research (2011)

  17. No Access

    Chapter and Conference Paper

    An Additional Pre-amplification Step for the Early Determination of Fetal RHD from Maternal Plasma

    The determination of the fetal RhD blood group is essential for the prevention of haemolytic disease of the newborn; prenatally it can be determined by genoty** fetal DNA. The advantage of fetal RHD genotype de...

    Tadeja Dovč-Drnovšek, Nataša Toplak in Circulating Nucleic Acids in Plasma and Se… (2011)

  18. Article

    Open Access

    Periodic fever syndromes in Eastern and Central European countries: results of a pediatric multinational survey

    To analyze the prevalence of diagnosed and suspected autoinflammatory diseases in Eastern and Central European (ECE) countries, with a particular interest on the diagnostic facilities in these countries.

    Nataša Toplak, Pavla Dolezalovà, Tamas Constantin, Anna Sedivà in Pediatric Rheumatology (2010)

  19. No Access

    Article

    Comparison of Genome Sequence of PVY Isolates with Biological Properties

    The whole RNA genomes of six European Potato virus Y (PVY) isolates, representing isolates of the PVYO, PVYN and PVYNTN subgroups, were sequenced and the reactions of a range of tobacco and potato cultivars after...

    Hugh Barker, Kara D. McGeachy, Nataša Toplak in American Journal of Potato Research (2009)

  20. No Access

    Protocol

    Expression Microarrays in Plant-Virus Interaction

    Since their conception in the late 1990s, microarray techniques have become a tool of choice for monitoring pangenomic gene expression. Although there are a large number of variations on the basic methodology ...

    Kristina Gruden, MaruŠa Pompe-Novak, špela Baebler in Plant Virology Protocols (2008)