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Adverse drug reaction-related hospitalisations among patients with heart failure at two hospitals in the United Arab Emirates
Background Little is known about the adverse drug reaction (ADR) related admissions among heart failure (HF) patients. Objective The aim of this study was to determine the rate, factors, ...
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Article
Open AccessIncidence of bladder cancer in Benghazi, Libya over the past three decades
There are limited data on the disease of bladder cancer in Libya. The objective of this study was to assess the pattern of incidence and clinical presentation of bladder cancer in Benghazi, Libya. This study w...
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Article
Open AccessPrediabetes and diabetes prevalence and risk factors comparison between ethnic groups in the United Arab Emirates
The economic growth has paralleled the rise of diabetes and its complications in multiethnic population of United Arab Emirates (UAE). Previous studies have shown that characteristics of diabetes is variable a...
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Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue
Besides lung drastic involvement, SARS-CoV-2 severely affected other systems including liver. Emerging epidemiological studies brought the attentions towards liver injury and impairment as a potential outcome ...
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Article
Open AccessUpregulation of interleukin-19 in saliva of patients with COVID-19
Cytokines are major players in orchestrating inflammation, disease pathogenesis and severity during COVID-19 disease. However, the role of IL-19 in COVID-19 pathogenesis remains elusive. Herein, through the an...
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Saliva metabolomic profile of COVID-19 patients associates with disease severity
Coronavirus disease 2019 (COVID-19) is strongly linked to dysregulation of various molecular, cellular, and physiological processes that change abundance of different biomolecules including metabolites that ma...
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Open AccessVitamin D enhances type I IFN signaling in COVID-19 patients
The ability of Vitamin D (VitD) to modulate antiviral responses through induction of antimicrobial peptide is well established. However, the effect of VitD on host responses to SARS-CoV-2 is not well investiga...
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Open AccessACE2 polymorphisms impact COVID-19 severity in obese patients
A strong association between obesity and COVID-19 complications and a lack of prognostic factors that explain the unpredictable severity among these patients still exist despite the various vaccination program...
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Hemizygous BTK Gene Variant Causing X-Linked Agammaglobulinemia in Two Siblings
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Open AccessIncreased blood immune regulatory cells in severe COVID-19 with autoantibodies to type I interferons
The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from poorly understood immunological dysfunction. While regulatory T (Treg) and B (Breg) cells, as the main elements of immun...