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Article
Open AccessPulmonary cancers across different histotypes share hybrid tuft cell/ionocyte-like molecular features and potentially druggable vulnerabilities
Tuft cells are chemosensory epithelial cells in the respiratory tract and several other organs. Recent studies revealed tuft cell-like gene expression signatures in some pulmonary adenocarcinomas, squamous cel...
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Article
Open AccessComplex hereditary peripheral neuropathies caused by novel variants in mitochondrial-related nuclear genes
Mitochondrial disorders are a group of clinically and genetically heterogeneous multisystem disorders and peripheral neuropathy is frequently described in the context of mutations in mitochondrial-related nucl...
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Article
Open AccessThe updated retrospective questionnaire study of sporadic inclusion body myositis in Japan
Sporadic inclusion body myositis (sIBM) is the most prevalent muscle disease in elderly people, affecting the daily activities. sIBM is progressive with unknown cause and without effective treatment. In 2015, ...
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Article
Spontaneous brain activity in the sensorimotor cortex in amyotrophic lateral sclerosis can be negatively regulated by corticospinal fiber integrity
Previous studies failed to detect reduced value of the amplitude of low frequency fluctuation (ALFF) derived from resting state functional magnetic resonance imaging in the primary motor cortex in amyotrophic ...
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Article
Open AccessMulticenter questionnaire survey for sporadic inclusion body myositis in Japan
Sporadic inclusion body myositis (sIBM) is the most prevalent acquired muscle disease in the elderly. sIBM is an intractable and progressive disease of unknown cause and without effective treatment. The etiolo...
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Article
Open AccessTransmission of survival signals through Delta-like 1 on activated CD4+ T cells
Notch expressed on CD4+ T cells transduces signals that mediate their effector functions and survival. Although Notch signaling is known to be cis-inhibited by Notch ligands expressed on the same cells, the role ...
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Article
Open AccessIncreased interleukin-17 in the cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease: a case-control study of rapidly progressive dementia
Inflammatory responses in the cerebrospinal fluid (CSF) of patients with sporadic Creutzfeldt-Jakob disease (sCJD) remain elusive.
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Article
Preparation of thin plate-like calcium phosphate particles with slit-shaped micropores and their molecular sieve effect
The formation of plate-like calcium phosphate particles with slit-shaped micropores produced from the forced hydrolysis reaction of 10 mM Ca(OH)2, 3.2 mM triphosphate(tripolyphosphate, tpp;
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Article
Preparation of porous yttrium oxide microparticles by gelation of ammonium alginate in aqueous solution containing yttrium ions
Porous Y2O3 microparticles 500 μm in size were obtained, when 1 wt%-ammonium alginate aqueous solution was dropped into 0.5 M-YCl3 aqueous solution by a Pasteur pipette and the resultant gel microparticles were h...
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Article
Effect of support on the conversion of methane to synthesis gas over supported iridium catalysts
A partial oxidation of methane was carried out using iridium catalysts supported on several metal oxides. The productivity of the synthesis gas from methane was strongly affected by the choice of support oxide...
